Background: Israeli population is primarily comprised of Jews (74%) and Arabs (21%). Previous studies suggested a higher incidence of cerebrovascular risk factors (CVRF) and dementia among Israeli Arabs. We evaluated potential cognitive disparities between community-dwelling Arabs and Jews diagnosed with at least one CVRF.
Method: 96 participants (age: 66.6± 5.3; education: 14.8± 4.1), 52 Arabs (age: 64.4± 5; education: 15.3±2.6), and 44 Jews (age: 69.1± 4.4; education: 14.8± 4.1) without known cognitive impairment and with at least one CVRF were prospectively enrolled. All participant completed a cognitive symptoms questionnaire (in their primary language) and underwent the Montreal Cognitive Assessment (MoCA) and the Tablet-based Cognitive Assessment Tool (TabCAT) Brain Health Assessment (BHA) battery, including the TabCAT Favorites (associative memory), Match (executive functions and processing speed) and Line Orientation (visuospatial skills) tasks. Demographic and clinical characteristics were analyzed using the Student's t-test for continuous variables and Chi-squared tests for categorical data.
Results: Arab participants were younger (p≤0.001) than Jews, education was similar (p = 0.26). Cognitive complaints were reported by 32 (33%) participants, (24% Arab,9% Jews). Participants with cognitive complaints exhibited significantly lower scores on Match (p = 0.005), but not on Favorites (p = 0.28), Line Orientation (p = 0.48), and MoCA (p = 0.62). Arabs scored significantly worse on Match (p = 0.006) while Jews scored worse on Line Orientation (p = 0.004). Performance was similar on the Favorites (p = 0.4) and MoCA (p = 0.2). When focusing on participants with cognitive complaints Arabs exhibited significantly lower scores on Match (p = 0.036) while Jews had lower scores on Line Orientation (p = 0.06). No significant differences were observed on Favorites (p = 0.4) or MoCA (p = 0.2). Among participants without cognitive complaints no significant differences were observed between Jews and Arabs on Match (p = 0.29), Favorites (p = 0.99) or MoCA (p = 0.65). Jews had lower scores on Line Orientation (p = 0.04).
Conclusion: TabCAT-BHA proved superior to MoCA in depicting subtle cognitive impairment in people with CVRF. Despite being younger, Arabs exhibited higher prevalence of cognitive complaints and were more impaired on executive functions while Jews on visuospatial tasks.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/alz.091749 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Clustering of > 145,000 symptom logs reveals distinct pre, peri, and menopausal phenotypes.
Sci Rep
January 2025
Opensci, LLC, Tucson, AZ, 85750, USA.
The transition to menopause is associated with disappearance of menstrual cycle symptoms and emergence of vasomotor symptoms. Although menopausal women report a variety of additional symptoms, it remains unclear which emerge prior to menopause, which occur in predictable clusters, how clusters change across the menopausal transition, or if distinct phenotypes are present within each life stage. We present an analysis of symptoms in premenopausal to menopausal women using the MenoLife app, which includes 4789 individuals (23% premenopausal, 29% perimenopausal, 48% menopausal) and 147,501 symptom logs (19% premenopausal, 39% perimenopausal, 42% menopausal).
View Article and Find Full Text PDFLower Urinary Tract Symptoms and Fall Risk: An Important Problem in Older Women with Cognitive Frailty.
Int Urogynecol J
January 2025
American Outpatient Medical Center, Department of Internal Medicine, Istanbul, Türkiye.
Introduction And Hypothesis: The objective of our study is to investigate the presence of lower urinary tract symptoms (LUTS) and its correlation with the risk of falling in older women with cognitive frailty.
Methods: The descriptive study was conducted on 102 female older adults, 60 women were classed as cognitively frail and 42 as healthy. Women were classified as having mild cognitive impairment based on the Clinical Dementia Rating Scale and as frail based on the Clinical Frailty Scale.
Basic Science and Pathogenesis.
Alzheimers Dement
December 2024
University of California, Irvine, Irvine, CA, USA.
Background: Subjective Memory Complaints (SMC) are defined as the perception of one's own memory. In several studies SMC are associated with Alzheimer's disease (AD) neuropathologic changes, and only one study has analyzed and found an association of SMC with other neurodegenerative, but not vascular, neuropathologic changes. Yet, the evidence on the association of SMC with non-AD neuropathologic changes is insufficient.
View Article and Find Full Text PDFBasic Science and Pathogenesis.
Alzheimers Dement
December 2024
Centre for Healthy Brain Ageing (CHeBA), University of New South Wales, UNSW Sydney, NSW, Australia.
Background: Subjective Cognitive Complaints (SCCs) can often precede mild cognitive impairment and dementia longitudinally. While increasingly considered an early prodromal stage of dementia, SCCs can also be a symptom of depression. Previous research found that SCCs in the absence of cognitive impairment, controlling for symptoms of depression, were moderately heritable and genetically associated with memory.
View Article and Find Full Text PDFClinical Manifestations.
Alzheimers Dement
December 2024
Department of Developmental and Educational Psychology, University of Santiago de Compostela, Santiago de Compostela, Spain.
Background: The importance of coincidence of cognitive complaints between participants without objective impairment and their informants in predicting progression remains unclear (Nosheny et al, 2022). Our objective was to determine whether agreement in dyadic reporting at baseline can predict survival time to progression to MCI or dementia.
Method: A sample of 145 participants from the CompAS Study was included in a survival analysis.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!