Clinical Manifestations.

Alzheimers Dement

Case Western Reserve University, Cleveland, OH, USA.

Published: December 2024

Background: A patient presented to movement disorder clinic with cognitive complaints, imbalance and prior diagnosis of NPH. The patient underwent ventriculoperitoneal shunt in the past with minimal improvement, a detailed history is suggestive of REM sleep behavioral disorder, autonomic dysfunction including orthostatic hypotension and urinary incontinence.

Method: Clinical evaluation was notable for bradykinesia, rigidity, truncal and cervical dystonia, shuffling steps, reduced arm swing bilaterally and pink, dusky skin of both hands.

Result: DaTscan showed reduced uptake of dopamine transporter.

Conclusion: Evaluation at movement disorder clinic helps early diagnosis of neurodegenerative disorders with subtle findings which allows patients to benefit from available treatments and participation in appropriate clinical trials.

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Source
http://dx.doi.org/10.1002/alz.093559DOI Listing

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