Background: This study assesses the sensitivity of the mobile cognitive app performance platform (mCAPP), a mobile and engaging cognitive assessment tool, to participant sleep duration.
Method: The mCAPP includes three gamified tasks: a memory task ("Concentration"), a stroop-like task ("Brick Drop"), and a digit-symbol coding-like task ("Space Imposters"). For all games, shorter reaction times and fewer guesses indicates better performance. The cohort included 50 participants (72% female; age = 71.9±4.5; education = 16.8±2.3; 51% white; 49% Black/African American) without cognitive impairment who are enrolled in the Penn ADRC cohort. Sleep data was collected via actigraphy (Fitbit). Game performance and overnight sleep prior to gameplay were analyzed as a whole and grouped by fewer (quartile 1; Q1) and higher (quartile 4; Q4) minutes of sleep.
Result: The average number of minutes of sleep was 378.0±96.5. Overall, minutes of sleep showed a significant negative correlation with reaction time on Space Imposters (ρ = 0.001). Participants with the fewest minutes of nighttime sleep performed slower than those with the most sleep on Space Imposters (Q1 M = 2.73; Q4 M = 2.40; p<.001), Brick Drop (Q1 M = 1.58; Q4 M = 1.31; p = .004), and Concentration (Q1 M = 5.25; Q4 M = 5.02; p = .006). There was not a significant difference in number of errors on Space Imposters (p = 0.53) or Brick Drop (p = 0.45) when comparing performance of participants with lower and higher quartiles of sleep, but there was a significant difference in the number of guesses on Concentration (Q1 M = 14.91; Q4 M = 12.80; p = 0.01).
Conclusion: The mCAPP can remotely detect differences in cognitive performance related to nighttime sleep prior to gameplay. Future studies will examine differences in performance related to the time-of-day gameplay occurs (how long after overnight sleep) and whether performance is affected by daytime napping. A larger data set will also be used to fully determine the sensitivity of mCAPP to participant sleep duration and examine within-participant effects.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/alz.093482 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effects of acupuncture and foot reflexology on sleep quality in patients with acute lymphoblastic leukemia: A clinical trial.
Explore (NY)
December 2024
Department of Medical-Surgical Nursing, School of Nursing and Midwifery, Maragheh University of Medical Sciences, Maragheh, Iran. Electronic address:
Background: Sleep disturbances are common among individuals with leukemia, and they can significantly impact their overall well-being. Acupuncture and foot reflexology, two alternative therapies rooted in traditional Chinese medicine, have gained recognition for their potential to address sleep issues and alleviate associated symptoms.
Methods: This single blinded, three-groups randomized controlled trial was navigated at Tohid Hospital, involving 132 leukemia patients divided into acupuncture (n = 44), foot reflexology (n = 44), and control (n = 44) groups via random card selection.
Behavioral and sociodemographic correlates of sleep duration among children in Samoa.
Sleep Health
January 2025
Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, Connecticut, USA.
Objectives: To describe sleep duration, adherence to sleep recommendations, and behavioral and sociodemographic correlates of sleep among Samoan children.
Methods: In a longitudinal cohort study of Samoan children aged 2-9years (n = 481; 50% female), primary caregivers reported usual number of hours of nighttime sleep during 2015, 2017/2018, and 2019/2020 data collection waves. Associations between behavioral and sociodemographic characteristics and sleep duration were assessed using generalized linear and mixed effect regressions.
Assessment of Craniofacial Growth Pattern Relative to Respiratory Mandibular Movement and Sleep Characteristics: A Pilot Study.
Eur J Dent
December 2024
Department of Orthodontics, School of Dental Medicine, State University of New York at Buffalo, Buffalo, New York, United States.
Objectives: The primary objective was to evaluate the influence of sagittal skeletal pattern on mandibular movement (MM) during sleep in growing orthodontic populations. The secondary objective was to compare MM according to obstructive sleep apnea (OSA) status.
Materials And Methods: This cross-sectional study included subjects between 6 and 17 years old, presenting with class I, II, and III skeletal patterns and no previous history of orthodontic treatment.
Clinical Manifestations.
Alzheimers Dement
December 2024
The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China.
Background: The study aimed to evaluate the effects of four weeks of 500 nm blue-green light visual stimulation on cognition, mood, and sleep in patients with subjective cognitive decline (SCD) and mild cognitive impairment (MCI).
Method: Eighty patients were recruited from the Memory Clinic. The experimental group comprised 42 cases (22 SCD and 20 MCI), while the control group comprised 38 cases (27 SCD and 11 MCI).
Clinical Manifestations.
Alzheimers Dement
December 2024
Cambridge Cognition, Cambridge, United Kingdom.
Background: Learning over repeated exposures (LORE) is an emerging paradigm that has shown sensitivity to AD biomarkers in apparently cognitively unimpaired (CU) samples using visual stimuli. We present results of a six-month study in a CU sample that explored brief (<2 minute) assessment of verbal LORE alongside other measures of memory and sleep.
Method: The Prolific platform was used to recruit 190 participants.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!