This letter aims to provide valuable insights into broader evidence triangulation (i.e., a well-designed primary association analysis followed by elaborate approaches to control residual confounding effects from various design and modeling perspectives) for clarifying the association between air pollutants and health outcomes. It also highlights the importance of selecting appropriate instrumental variable for instrument-based causal modeling, emphasizing that all causal questions can be effectively addressed within the Mendelian randomization framework.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11696255 | PMC |
CNS Neurosci Ther
January 2025
Department of Biostatistics, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu, China.
This letter aims to provide valuable insights into broader evidence triangulation (i.e., a well-designed primary association analysis followed by elaborate approaches to control residual confounding effects from various design and modeling perspectives) for clarifying the association between air pollutants and health outcomes.
View Article and Find Full Text PDFSubst Abuse Treat Prev Policy
December 2024
Department of Preventive Medicine, Universidade Federal de São Paulo, Rua Botucatu, N 740 - Vila Clementino, São Paulo, SP, 04023-062, Brazil.
Background: The widely implemented prevention program in Brazil, PROERD (a translated version of the DARE-kiR program), showed no evidence of effect in preventing drug use in a recent trial. The lack of cultural adaptation and instructors' deviations from the curriculum were identified as potential reasons for its ineffectiveness. This study aims to identify points of inadequacy of the PROERD program for the Brazilian culture, suggesting strategies for revising the curriculum to improve implementation.
View Article and Find Full Text PDFComput Brain Behav
December 2024
Department of Communication, University of California, Los Angeles, Los Angeles, CA USA.
In many scientific fields, sparseness and indirectness of empirical evidence pose fundamental challenges to theory development. Theories of the evolution of human cognition provide a guiding example, where the targets of study are evolutionary processes that occurred in the ancestors of present-day humans. In many cases, the evidence is both very sparse and very indirect (e.
View Article and Find Full Text PDFJ Geriatr Phys Ther
December 2024
School of Psychology and Public Health, La Trobe University, Victoria, Australia.
Background And Purpose: Motivational interviewing, an evidence-based person-centered counseling style, may help to facilitate increased mobility and physical activity after hip fracture. We explored contextual factors influencing the outcome, mechanism, and implementation of motivational interviewing after hip fracture.
Methods: A qualitative study was completed using an interpretive description framework.
Palliat Care Soc Pract
December 2024
Vrije Universiteit Brussel (VUB) & Ghent University, End-of-Life Care Research Group, Brussels, Belgium.
Background: Older people who die from serious chronic disease typically experience long periods (months or years) of illness and complex fluctuations in their physical health and in their social, psychological and existential well-being. Our understanding of these end-of-life trajectories is very limited, focuses predominantly on physical function and clinical predictors and neglects inter-individual differences. A better understanding of end-of-life trajectories, including what is shared among people and what is individually specific, is needed for an optimal provision of palliative care and health services planning.
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