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http://dx.doi.org/10.3389/fncom.2024.1523973 | DOI Listing |
NPJ Parkinsons Dis
January 2025
Movement Disorders Unit, Neurological Institute, Tel Aviv Medical Center, Tel Aviv, Israel.
Alpha-synuclein (αS) aggregation is a widely regarded hallmark of Parkinson's disease (PD) and can be detected through synuclein amplification assays (SAA). This study investigated the association between cerebrospinal fluid (CSF) radiological measures in 41 PD patients (14 iPD, 14 GBA1-PD, 13 LRRK2-PD) and 14 age-and-sex-matched healthy controls. Quantitative measures including striatal binding ratios (SBR), whole-brain and deep gray matter volumes, neuromelanin-MRI (NM-MRI), functional connectivity (FC), and white matter (WM) diffusion-tensor imaging (DTI) were calculated.
View Article and Find Full Text PDFFront Comput Neurosci
December 2024
Biomedical Image Processing (BIP) Lab, Department of Computing, Federal University of São Carlos, São Carlos, Brazil.
Front Neural Circuits
January 2025
Federal Center of Brain Research and Neurotechnologies, Moscow, Russia.
According to the World Health Organization, the number of people suffering from depressive disorders worldwide is approaching 350 million. The consequences of depressive disorders include considerable worsening of the quality of life, which frequently leads to social isolation. One of the key factors which may cause depression in adulthood is early life stress, in particular, insufficient maternal care during infancy.
View Article and Find Full Text PDFJ Psychosoc Nurs Ment Health Serv
January 2025
University of Washington, School of Nursing, Biobehavioral Nursing, and Health Informatics, Seattle, Washington.
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