Introduction The Meds to Beds (MTB) program aims to enhance medication adherence and reduce hospital readmissions by delivering prescribed medications directly to patients' bedsides before discharge. This study evaluated the effectiveness of the MTB program in reducing 90-day readmission rates in a community teaching hospital. Methods This prospective study was conducted at a 159-bed community teaching hospital in Boston, MA. The study included 63 patients discharged from emergency, medical, or surgical units with at least one newly prescribed medication. Patients served as their own controls, with readmission rates compared to 90 days before and after the MTB intervention. Data were collected from electronic medical records, and paired t-tests were used to assess statistical significance, with a p-value <0.05 was used to determine statistical significance. Principal findings The study included 63 patients who received their medications before discharge. The mean number of admissions significantly decreased from 1.52 pre-intervention to 0.47 post-intervention (p < 0.001). Key interventions included prescription retrieval, addressing medication access barriers, and bedside delivery with personalized counseling. Conclusions The implementation of the MTB program significantly reduced hospital readmissions, improved medication adherence, and enhanced patient satisfaction. Addressing barriers such as transportation, high copays, and pharmacy accessibility empowered patients to adhere to prescribed regimens. This study highlights the potential benefits of expanding the MTB program to other healthcare settings to enhance care quality and reduce readmission rates.
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http://dx.doi.org/10.7759/cureus.76744 | DOI Listing |
J Cancer Res Clin Oncol
January 2025
Sarcoma Unit, Department of Surgery, University Medical Center and Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Purpose: The management of soft tissue sarcoma (STS) at reference centers with specialized multidisciplinary tumor boards (MTB) improves patient survival. The German Cancer Society (DKG) certifies sarcoma centers in German-speaking countries, promoting high standards of care. This study investigated the variability in treatment recommendations for localized STS across different German-speaking tertiary sarcoma centers.
View Article and Find Full Text PDFEur J Clin Microbiol Infect Dis
January 2025
Department of Ultrasound Medicine, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510150, China.
Background: Public health issues related to tuberculosis still exist. Because Xpert MTB/RIF Ultra is more effective than conventional TB diagnostic techniques are, it is now regarded as an emerging technology. The diagnostic accuracy of Xpert MTB/RIF Ultra for tuberculosis was assessed in this systematic study.
View Article and Find Full Text PDFCureus
January 2025
Cardiology, St. Elizabeth's Medical Center, Boston, USA.
Introduction The Meds to Beds (MTB) program aims to enhance medication adherence and reduce hospital readmissions by delivering prescribed medications directly to patients' bedsides before discharge. This study evaluated the effectiveness of the MTB program in reducing 90-day readmission rates in a community teaching hospital. Methods This prospective study was conducted at a 159-bed community teaching hospital in Boston, MA.
View Article and Find Full Text PDFNat Commun
January 2025
Department of Internal Medicine and Radboud Community for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, the Netherlands.
Some individuals, even when heavily exposed to an infectious tuberculosis patient, do not develop a specific T-cell response as measured by interferon-gamma release assay (IGRA). This could be explained by an IFN-γ-independent adaptive immune response, or an effective innate host response clearing Mycobacterium tuberculosis (Mtb) without adaptive immunity. In heavily exposed Indonesian tuberculosis household contacts (n = 1347), a persistently IGRA negative status was associated with presence of a BCG scar, and - especially among those with a BCG scar - with altered innate immune cells dynamics, higher heterologous (Escherichia coli-induced) proinflammatory cytokine production, and higher inflammatory proteins in the IGRA mitogen tube.
View Article and Find Full Text PDFSci Adv
January 2025
Department of Biological Engineering, MIT, Cambridge, MA, USA.
Intradermal Bacillus Calmette-Guérin (BCG) is the most widely administered vaccine, but it does not sufficiently protect adults against pulmonary tuberculosis. Recent studies in nonhuman primates show that intravenous BCG administration offers superior protection against (). We used single-cell analysis of bronchoalveolar lavage cells from rhesus macaques vaccinated via different routes and doses of BCG to identify alterations in the immune ecosystem in the airway following vaccination.
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