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Experiences of perinatal genetic screening for people from migrant and refugee backgrounds: a scoping review.
Eur J Hum Genet
January 2025
Murdoch Children's Research Institute, Melbourne, VIC, Australia.
People from refugee and migrant backgrounds often face poor experiences and outcomes in healthcare, and genetic healthcare is no exception. Understanding whether and how these health inequities manifest is an important step towards equitable perinatal genetic screening for genetic or chromosomal conditions (offered preconception, prenatally, or during the newborn period). A scoping review was conducted to review international evidence of perceptions and experiences of perinatal genetic screening for people from migrant and refugee backgrounds.
View Article and Find Full Text PDFCarpal tunnel syndrome diagnosis as a risk factor for falls.
Int Orthop
January 2025
Stanford Medicine, Stanford, CA, USA.
Purpose: Subclinical peroneal neuropathy without overt foot drop has been linked to increased fall risk in adults, yet remains under reported due to subtle symptoms and lack of awareness. Patients with carpal tunnel syndrome (CTS) often experience other nerve entrapments, prompting this study to evaluate CTS (a proxy for peroneal nerve entrapment) as a significant predictor of time to first fall.
Methods: Data from the Merative MarketScan Research Databases (2007-2021) were used to identify adult patients using ICD-9/10 codes.
Unravelling situational awareness of multi-tasking pedestrians through average gaze fixation durations: An accelerated failure time modelling approach.
Accid Anal Prev
January 2025
Department of Civil Engineering, Indian Institute of Technology Roorkee, Roorkee, 247667, India. Electronic address:
Pedestrians use visual cues (i.e., gaze) to communicate with the other road users, and visual attention towards the surrounding environment is essential to be situationally aware and avoid oncoming conflicts.
View Article and Find Full Text PDFPD-L1 testing patterns in recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC) in the U.S.
Oral Oncol
January 2025
Value and Implementation, Outcomes Research, Merck & Co., Inc., 126 East Lincoln Avenue, Rahway, NJ 07065, USA.
Background: Pembrolizumab with/without platinum + 5-FU is approved for the first-line (1L) treatment of R/M HNSCC, and its monotherapy use requires PD-L1 Combined Positive Score (CPS) ≥ 1. We aimed to understand PD-L1 testing patterns and associations with patient characteristics and treatment choice in R/M HNSCC.
Methods: Adults with R/M HNSCC initiating 1L systemic therapy were included from a U.
Multi-scale multi-object semi-supervised consistency learning for ultrasound image segmentation.
Neural Netw
December 2024
Department of Mechanical Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore 117575, Singapore. Electronic address:
Manual annotation of ultrasound images relies on expert knowledge and requires significant time and financial resources. Semi-supervised learning (SSL) exploits large amounts of unlabeled data to improve model performance under limited labeled data. However, it faces two challenges: fusion of contextual information at multiple scales and bias of spatial information between multiple objects.
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