Mycosis fungoides (MF) is a neoplasm of the immune system. It is a cutaneous lymphoma originating in the peripheral epidermotropic T-cells, specifically the memory T-cells (CD45RO+). The etiology of MF is indefinite, but various factors, such as genetic and epigenetic abnormalities, environmental and occupational exposure to chemicals, infections, and cytokines (interleukin [IL]-2, IL-4, etc.), play a vital role. Pityriasis lichenoides (PL), such as MF, is a rare subtype that is presented with skin lesions similar to that of PL.
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Pityriasis Lichenoides Chronica-Like Mycosis Fungoides: A Diagnostic Dilemma.
Skinmed
January 2025
Department of Skin & VD, Civil Hospital, BJ Medical College, Ahmedabad, Gujarat, India.
Mycosis fungoides (MF) is a neoplasm of the immune system. It is a cutaneous lymphoma originating in the peripheral epidermotropic T-cells, specifically the memory T-cells (CD45RO+). The etiology of MF is indefinite, but various factors, such as genetic and epigenetic abnormalities, environmental and occupational exposure to chemicals, infections, and cytokines (interleukin [IL]-2, IL-4, etc.
View Article and Find Full Text PDFTwo cases of pityriasis lichenoides chronica successfully treated with methotrexate injection and upadacitinib, respectively.
Eur J Dermatol
October 2024
Department of Dermatology, The Fifth Affiliated Hospital, Sun Yat-sen University, 52 Meihua East Rd, Zhuhai, China.
Introduction: Lymphocytic esophagitis (LyE) is a rare esophageal disorder of unknown etiology, characterized by dense peripapillary lymphocytes without neutrophils or eosinophils, and spongiosis. Patients typically present with symptoms such as dysphagia or chest pain. Here, we describe a notable case of lymphocytic esophagitis in a patient who presented with food impaction.
View Article and Find Full Text PDFA clinical case of pityriasis lichenoides chronica presenting with palpable purpura after streptococcal infection.
Folia Med (Plovdiv)
June 2024
Sofiamed University Hospital, St Kliment Ohridski University, Sofia, Bulgaria.
Article Synopsis
- Pityriasis lichenoides is a rare inflammatory skin condition characterized by red-brown papules and crusty lesions as they evolve over time.
- A 60-year-old woman developed the chronic form of this condition ten days after suffering from streptococcal pharyngitis, starting with purple spots on her legs and later developing red, scaly patches on other parts of her body.
- After treatment with methylprednisolone and hydroxychloroquine, her skin lesions improved significantly and did not return.
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