A relative paucity of published papers is observed regarding racial and ethnic disparities in cutaneous T cell lymphoma (CTCL). Although CTCL is a rare condition, the poor outcomes associated with this condition underscore the need to understand and address any existing care inequities. Recently, a growing body of literature has attempted to identify racial disparities in CTCL in terms of the overall survival, stage at presentation, time to initiate treatment, and complication rate. Some progress has been made in understanding the underlying causes of such disparities, with some proposing the biologic and genetic differences between Caucasian and black patients, others proposing that environmental exposure to chemicals, such as benzene, may predispose certain populations to the disease, and still others suggesting that other factors related to socioeconomic status, such as insurance type, may play a role. We review what is known about racial and ethnic differences in clinical presentations, existing health disparities, key hypotheses regarding drivers of these trends, and actionable strategies to address these disparities.
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Skinmed
January 2025
Division of Dermatology, UCLA Medical Center, Los Angeles, CA.
A relative paucity of published papers is observed regarding racial and ethnic disparities in cutaneous T cell lymphoma (CTCL). Although CTCL is a rare condition, the poor outcomes associated with this condition underscore the need to understand and address any existing care inequities. Recently, a growing body of literature has attempted to identify racial disparities in CTCL in terms of the overall survival, stage at presentation, time to initiate treatment, and complication rate.
View Article and Find Full Text PDFAnn Allergy Asthma Immunol
December 2024
The Mount Sinai Hospital, New York, NY, USA.
Background: Hereditary angioedema (HAE) is clinically characterized by recurrent attacks of cutaneous and submucosal swelling.
Objective: To investigate real-world timing, potential barriers, and impact of delaying on-demand treatment (OD) of HAE attacks METHODS: Patients with HAE (type I or II) aged ≥12 years with ≥1 treated (Treated Cohort) or untreated (Untreated Cohort) attack in the past 3 months were recruited by the US HAE Association. Respondents completed a 20-minute, self-reported, online survey about their last HAE attack.
Br J Dermatol
December 2024
The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia.
Background: Cutaneous T-cell lymphomas (CTCL) are rare with distinct diagnostic challenges. Equitable access to cancer care is a recognised priority, internationally. To date, the geospatial distribution of CTCL has not been definitively studied.
View Article and Find Full Text PDFSemin Radiat Oncol
January 2025
Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Department of Radiology, The University of Melbourne, Parkville, Victoria, Australia; Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
Cutaneous T-cell lymphomas (CTCL) are a rare collection of diseases, frequently associated with diagnostic challenges and complex management dilemmas. The multidisciplinary team is vital for accurate clinico-pathological diagnoses and for collaborative therapeutic decisions throughout the management journey, which frequently involves multiple lines of therapy. Radiotherapy (RT) is a highly effective skin-directed therapy for CTCL, commonly delivered as localised fields or as total skin electron beam therapy (TSEBT).
View Article and Find Full Text PDFJ Surg Oncol
December 2024
Division of Health Services Research, Institute for Cancer Control, National Cancer Center, Tokyo, Japan.
Malignant cutaneous adnexal tumors (MCATs) are rare. Previous population-based studies to determine the clinical features and prognosis of MCATs mainly included Caucasian patients, and the characteristics of Asian patients with MCATs have not yet been investigated. We aimed to investigate the characteristics of Asian patients with MCAT using a Japanese database.
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