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Intrapleural fibrinolytic therapy for pleural infections: Outcomes from a cohort study.
Ann Acad Med Singap
December 2024
Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore.
Introduction: Pleural infections are a significant cause of mortality. Intrapleural fibrinolytic therapy (IPFT) utilising alteplase and dornase is a treatment option for patients unsuitable for surgery. The optimal dose of alteplase is unknown, and factors affecting treatment success in an Asian population are unclear.
View Article and Find Full Text PDFIntrapleural fibrinolytic therapy: How low can we get?
Ann Acad Med Singap
December 2024
Department of Respiratory and Critical Care Medicine, Ng Teng Fong Hospital, Singapore.
The Risk of Pneumothorax With Intrapleural Urokinase in Children With Parapneumonic Effusion.
Pediatr Pulmonol
December 2024
Faculty of Medicine and Health Science, Tel Aviv University, Tel Aviv, Israel.
Aim: Fibrinolytic therapy is commonly used in children with parapneumonic effusion, to facilitate drainage of the effusions and recovery. However, data regarding complications of this treatment in children are limited. We aimed to determine the incidence of pneumothorax (PNX) associated with intrapleural urokinase.
View Article and Find Full Text PDFUltrasound-guided management of tuberculosis-related pleural effusion in a pediatric patient: A case report and literature review.
Radiol Case Rep
January 2025
Pediatric Clinic and Rare Diseases, Microcitemico Hospital "A. Cao", University of Cagliari, Cagliari, Italy.
Tuberculosis (TB) remains a significant global health challenge, particularly within pediatric populations. This article reports the case of a 7-year-old female patient admitted with massive fibrinous pleural effusion secondary to TB, highlighting the key role of ultrasound in disease monitoring and therapeutic guidance. The patient presented with fever, cough, and abdominal pain.
View Article and Find Full Text PDF[Not Available].
Ugeskr Laeger
October 2024
Lungemedicinsk Forskningsenhed (PLUZ, SUH), Syddansk Universitet.
Article Synopsis
- Fast and accurate diagnosis and treatment of pleural infections can significantly lower mortality rates, highlighting the importance of starting treatment quickly and monitoring it regularly.
- Advanced therapies, such as intrapleural fibrinolytic therapy, should be carried out in specialized medical departments.
- In Denmark, there's an urgent need to improve the speed of diagnostic procedures and treatment for pleural infections to enhance patient outcomes.
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