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http://dx.doi.org/10.1136/pn-2024-004382DOI Listing

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Article Synopsis
  • Infratentorial superficial siderosis (iSS) is a neurological disorder caused by iron deposits on the brain and spinal cord due to ongoing bleeding.
  • This condition often leads to symptoms like hearing loss, balance issues, and problems with coordination and movement.
  • The article emphasizes the need for a multidisciplinary approach to diagnose and manage the complex challenges associated with iSS effectively.
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MRI-Based Prediction of Macrovascular Causes of Intracerebral Hemorrhage: The MACRO Score.

Neurology

November 2024

From the Department of Neurology (S.F.-H., L.O., M.K., C.E., T.G.), Medical University of Graz, Austria; Department of Statistical Science (G.A.), University College London, United Kingdom; Department of Neurology (M.B.G., D.J.S.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Institute for Medical Informatics, Statistics and Documentation (G.W.), Medical University of Graz, Austria; Stroke Research Centre (S.F.-H., W.Z., Y.D., M.L., H.O., P.S.N., L.P., R.M., K.T., R.J.S., D.J.W.), Department of Brain Repair & Rehabilitation, UCL Queen Square Institute of Neurology, United Kingdom; Division of Neuroradiology, Vascular and Interventional Radiology (O.N.), Department of Radiology, Medical University of Graz, Austria; and Neuroradiological Academic Unit (H.R.J.), Department of Brain Repair & Rehabilitation, UCL Queen Square Institute of Neurology, United Kingdom.

Article Synopsis
  • A significant portion of spontaneous intracerebral hemorrhages (ICH) arise from macrovascular causes, necessitating a swift diagnosis, often through invasive procedures like digital subtraction angiography (DSA), which aren't suitable for all patients.
  • This study aimed to develop a new risk stratification score, the MACRO score, incorporating MRI findings to improve the identification of macrovascular causes of ICH.
  • The MACRO score successfully incorporates various patient factors and MRI markers, demonstrating better predictive capabilities than current CT-based scores, validating its effectiveness in a diverse patient population.
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CT angiography-source image (CTA-SI) can be used as an effective alternative to diffusion-weighted imaging (DWI) for identifying acute ischemic stroke (AIS). This study investigates the reliability of combining CTA-SI with non-contrast CT (NCCT) for AIS diagnosis, with a focus on how different brain areas affect diagnostic accuracy. Patients with various subtypes of AIS who underwent NCCT, CTA, and DWI from January to December 2022 were included.

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Article Synopsis
  • - Superficial siderosis is a rare neurodegenerative disease caused by the buildup of hemosiderin in the brain due to ongoing bleeding in the subarachnoid space, often following older cranio-spinal injuries or surgeries.
  • - There are three main types of superficial siderosis, with symptoms including progressive ataxia and deafness; early diagnosis is crucial to prevent severe complications requiring surgery.
  • - The case series focuses on showcasing both acute and chronic effects of superficial siderosis, highlighting unique imaging signs that aid in early detection and timely treatment.
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