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| http://dx.doi.org/10.1161/CIRCRESAHA.124.325805 | DOI Listing |
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Stick to the Script: How Endomucin Keeps the Glycocalyx in Line.
Circ Res
January 2025
Department of Medicine, Vanderbilt University Medical Center, Nashville, TN (R.M., A.K.).
Sticking to the script: Breast cancer patients' decision making regarding oral endocrine therapy.
Patient Educ Couns
October 2024
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, NC, USA; Division of Hematology and Oncology, University of North Carolina at Chapel Hill, NC, USA.
Objectives: We sought to understand why some women with early-stage breast cancer decide to forgo or discontinue endocrine therapy (ET), and to identify factors that might lead to greater acceptance of, and long-term adherence to, this treatment.
Methods: We conducted in-depth interviews with N = 53 stage I-III HR+ women who were either non-initiators of ET, initiators who discontinued or initiators who continued with variable daily patterns of adherence. An inductive content analysis was performed to explore the decision-making process of women prescribed ET.
A dataset of EEG recordings from 47 participants collected during a virtual reality working memory task where attention was cued by a social avatar and non-social stick cue.
Data Brief
April 2022
Institute of Health and Neurodevelopment, Aston Laboratory for Immersive Virtual Environments, Aston University, UK.
This data article describes electroencephalography (EEG) and behavioral data from 47 participants. Data was collected using a 64 channel eego™ sports mobile EEG system during a visual working memory task presented in virtual reality (VR) using Unity with an Oculus Rift S head-mounted display. In the memory task, participants had to remember the status of and details about objects presented on a table.
View Article and Find Full Text PDFONQUADRO: a database of experimentally determined quadruplex structures.
Nucleic Acids Res
January 2022
Institute of Computing Science, Poznan University of Technology, 60-965 Poznan, Poland.
ONQUADRO is an advanced database system that supports the study of the structures of canonical and non-canonical quadruplexes. It combines a relational database that collects comprehensive information on tetrads, quadruplexes, and G4-helices; programs to compute structure parameters and visualise the data; scripts for statistical analysis; automatic updates and newsletter modules; and a web application that provides a user interface. The database is a self-updating resource, with new information arriving once a week.
View Article and Find Full Text PDFModeling of Adhesion in Tablet Compression at the Molecular Level Using Thermal Analysis and Molecular Simulations.
Mol Pharm
January 2022
Department of Pharmaceutical Sciences, Arnold and Marie Schwartz College of Pharmacy, Long Island University, 75 Dekalb Avenue, Brooklyn, New York 11201, United States.
The molecular basis of adhesion leading to sticking was investigated by exploring the correlation between thermal analysis and molecular simulations. It is hypothesized that intermolecular interactions between a drug molecule and a punch face are the first step in the adhesion process and the rank order of adhesion during tablet compression should correspond to the rank order of the energies of these interactions. In the present study, the sticking propensity was investigated using ibuprofen, flurbiprofen, and ketoprofen as model substances.
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