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Efficient and reproducible differentiation protocol for pluripotent stem cells into functional endothelial cells: Unveiling the path to vascular regeneration.
Arch Med Res
January 2025
Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, Tehran, Iran; Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, Tehran, Iran.
Introduction: Endothelial cells (ECs) play a crucial role in many treatments for cardiovascular diseases, such as blood vessel repair, tissue engineering, and drug delivery. The process of differentiating these cells is complex and involves various sources and numerous molecular and cellular events. Differentiating pluripotent stem cells (PSCs) into endothelial cells are one of the most effective sources for creating ECs in the lab and offers great potential for regenerative medicine.
View Article and Find Full Text PDFMultifunctions of Sustainable Chondroitin Sulfates with Predominant Subtypes and Low Molecular Weights on Neurite Outgrowth.
Biomacromolecules
January 2025
School of Life Science and Health Engineering, Jiangnan University, Wuxi 214122, China.
Three chondroitin sulfate (CS) analogues with predominant subtypes (A, C, and E) were prepared from engineered K4 combined with regioselective sulfation. CS with the designed sulfates as the main components was characterized by nuclear magnetic resonance spectroscopy, elementary analysis, and disaccharide analysis. CS prepared from the native or degraded capsular polysaccharide had molecular weights of 1.
View Article and Find Full Text PDFStudy on the vibration characteristics and influence range of buried dam pipeline.
Sci Rep
January 2025
China Institute of Water Resources and Hydropower Research, Beijing, 100038, China.
To alleviate water resource shortages and tensions and meet the water diversion needs of different river basins, buried (cross-dam) pipelines have become an essential component of water diversion projects. They are installed in levee projects in key river basins such as the Yellow River, Jingjiang River, and Beijiang River. Due to the complex engineering structure and multiple sources of vibration excitation, if vibrations propagate along the pipeline axis towards the surrounding levee, they could have an adverse impact on the stability and safe operation of the levee.
View Article and Find Full Text PDFWomen's experiences of living with adenomyosis and perceptions of the diagnostic journey: a scoping review.
BMJ Open
January 2025
School of Health Sciences, University of Dundee, Dundee, UK.
Objectives: Uterine adenomyosis is a common gynaecological disease that can be debilitating. It is poorly understood and may be overlooked in clinical settings. A research gap exists as there are currently no published scoping reviews on perceptions and experiences early in the illness course.
View Article and Find Full Text PDFA two-wave survey study examining the impact of different sources of pregnancy information on pregnancy-related anxiety among Swedish women.
Eur J Midwifery
January 2025
Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Introduction: During pregnancy, women rely on a variety of sources to obtain information. However, not all of these sources are equally reliable, and there is the concern that especially online information-seeking may increase pregnancy-related anxiety. This study examines to what extent different sources of pregnancy information are associated with concurrent pregnancy-related anxiety (RQ1) and changes in pregnancy-related anxiety throughout the pregnancy (RQ2).
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