Utilization of maternal and child interventions is typically tracked in low- and middle-income countries (LMICs) using coverage estimates from population representative surveys. These estimates cannot be directly applied to assess resource gaps in intervention delivery for which data on the population eligible is required. Moreover, coverage improvements may not necessarily reflect an expansion in utilization because of a decline in the population eligible. We develop a method to estimate the populations eligible for interventions across the continuum of care. The method uses data from the World Population Prospects and the Demographic Health Survey, data sources which are available for most LMICs. Additionally, we develop a method to estimate the eligible population covered by each intervention. Using the illustration of India, we estimate populations eligible for, and covered by interventions during preconception, pregnancy, delivery, lactation, and childhood. We find that between 2015 and 2020, the eligible population declined for all beneficiary groups. Additionally, coverage expansion was not entirely driven by an increase in the population accessing an intervention, but rather also by a decline in the eligible population. Our illustration highlights the importance of including population estimates alongside coverage for interventions, particularly in LMIC contexts due to changing fertility dynamics.
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http://dx.doi.org/10.1093/aje/kwae469 | DOI Listing |
AIDS Res Ther
January 2025
University of Khartoum, Khartoum, Sudan.
Background: Thyroid disorders have significant clinical sequelae, including impaired growth in children, metabolic abnormalities, and impaired cognitive function. However, available studies on burden of thyroid diseases in people with human immunodeficiency virus (HIV), particularly its prevalence and its interaction with HIV related factors (like CD4 count), are controversial. This review aimed to provide a comprehensive summary and analysis on the extent of thyroid dysfunctions in this population.
View Article and Find Full Text PDFBMJ Open Gastroenterol
January 2025
Biomedical Sciences, Wollo University, Dessie, Ethiopia.
Objective: Gallstone disease is a prevalent global health issue, but its impact in Africa remains unclear. This study aims to summarise and synthesise available data on the prevalence of gallstone disease across populations in Africa.
Design: Systematic review and meta-analysis, reported in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines.
ESMO Open
January 2025
Division of Oncology, Department of Medicine I, Medical University Vienna, Vienna, Austria. Electronic address:
Background: Ethnic diversity in cancer clinical trials is essential to ensure that therapeutic advances are equitable and broadly applicable in multicultural societies. Yet, missing consensus on the documentation of ethnic origin, partially based on the complexity of the terminology and fear of discrimination, leads to suboptimal patient management of minority populations. Additionally, eligibility criteria, such as stringent laboratory cut-offs, often fail to account for variations across ethnic groups, potentially excluding patients without evidence-based justification.
View Article and Find Full Text PDFSemin Arthritis Rheum
December 2024
Department of Medicine, Division of Rheumatology, Maastricht University Medical Centre+, Maastricht, the Netherlands; Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, the Netherlands.
Objective: To systematically review operational definitions of old(er) age in rheumatoid arthritis (RA) patients and investigate differences in disease-modifying anti-rheumatic drug (DMARD) efficacy, safety and drug survival between young(er) and old(er) patients.
Methods: A systematic review was performed on studies conducting research in an old(er) RA patient population. Two reviewers independently performed data extraction and risk of bias assessment.
Breast
January 2025
Department of Plastic Surgery, Copenhagen University Hospital, Herlev and Gentofte, Denmark; Department of Clinical Medicine, University of Copenhagen, Denmark.
Aim/background: Patient-reported outcome measurement instruments are important tools in understanding a breast reconstruction's impact on the patients' quality of life. A psychometric validation is essential before applying a patient-reported outcome measurement instrument in clinical practice and research. The BREAST-Q is a specific, validated questionnaire for breast surgery outcomes that has been translated from English to Danish.
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