AI Article Synopsis

  • A three-step scale called DICA was evaluated for its ability to predict diverticular disease in patients without symptoms during colorectal cancer screening.
  • In a study involving 3,879 participants, 24.7% were found to have diverticula, but the DICA scale did not show any significant relationship with the occurrence of diverticulitis or hospital admissions.
  • The study concluded that DICA has limited predictive value for diverticulitis, highlighting the need for further research with larger groups.

Article Abstract

Introduction: Recently, a three-step endoscopic scale, known as the Diverticular Inflammation and Complication Assessment (DICA), was introduced to predict the course of diverticular disease (DD), yielding some promising outcomes. However, analyses were performed only for symptomatic individuals.

Objectives: The aim of our study was to prospectively evaluate the predictive value of DICA in asymptomatic individuals with no previous diagnosis of DD who underwent colorectal cancer screening colonoscopy.

Patients And Methods: We performed a prospective cohort study. All consecutive individuals, aged 55-65, undergoing screening colonoscopy in a single center during a 6-month period were assessed for eligibility. Those with diverticulosis were followed-up for 12 months. Information on the course of the disease, symptoms, treatment, diverticulitis episodes confirmed by healthcare professionals, complications, and hospital admissions was obtained via telephone interviews conducted by doctors. Detailed data and medical conditions were evaluated.

Results: Out of 3,879 participants, 958 (24.7%) had diverticula. Of these, 872 (49.8% females, mean age 61 years) completed the study. About 83.5%, 12.85%, and 3.67%  of patients were classified as DICA1, DICA2, and DICA3, respectively. Diverticulitis occurred in 12 (1.37%) patients. Hospital admission was needed in five patients. No surgical interventions were necessary. There were no statistically significant relationship between DICA score and diverticulitis or hospital admission. Previous abdominal surgery and appendectomy, the presence and severity of pain, bloating, and previous DD treatment were the only factors predisposing to diverticulitis.

Conclusions: In our cohort, DICA scale had no predictive value for the occurrence of diverticulitis. Hence, has a limited predictive value for occurrence of diverticulitis and more studies on bigger cohorts are necessary to test its usefulness.

Download full-text PDF

Source
http://dx.doi.org/10.20452/pamw.16915DOI Listing

Publication Analysis

Top Keywords

diverticular inflammation
8
inflammation complication
8
complication assessment
8
asymptomatic individuals
8
hospital admission
8
predictive occurrence
8
occurrence diverticulitis
8
diverticulitis
6
assessment predict
4
predict diverticulitis
4

Similar Publications

Article Synopsis
  • A three-step scale called DICA was evaluated for its ability to predict diverticular disease in patients without symptoms during colorectal cancer screening.
  • In a study involving 3,879 participants, 24.7% were found to have diverticula, but the DICA scale did not show any significant relationship with the occurrence of diverticulitis or hospital admissions.
  • The study concluded that DICA has limited predictive value for diverticulitis, highlighting the need for further research with larger groups.
View Article and Find Full Text PDF

Diverticulitis is a relatively common condition in gastroenterology. It is most often presented by inflammation of one or more diverticula, depending on their presence in the colon, and by abdominal pain and bleeding. Bleeding from the diverticulum has a wide range of clinical manifestations, which in a certain percentage of cases can have a very unfavorable course and prognosis.

View Article and Find Full Text PDF

Complicated diverticulitis: Diagnostic precision and surgical solutions in a patient with chronic kidney disease.

Radiol Case Rep

January 2025

Northeast Georgia Health System, Northeast Georgia Medical Center, Trauma and Acute Care Surgery Department, 743 Spring Street NE Gainesville, GA 30501.

Diverticulitis, an inflammation of diverticula in the colon, can lead to severe complications such as perforation and abscess formation. A 42-year-old female with polycystic kidney disease and chronic kidney disease stage III presented with severe abdominal pain, fever, and inability to tolerate oral intake. The patient was a previous smoker who smoked 0.

View Article and Find Full Text PDF

Colorectal cancer (CRC) remains challenging to diagnose, necessitating the identification of a noninvasive biomarker that can differentiate it from other conditions such as inflammatory bowel diseases (IBD) and diverticular disease (DD). Raman spectroscopy (RS) stands out as a promising technique for monitoring blood biochemical profiles, with the potential to identify distinct signatures identifying CRC subjects. We performed RS analysis on dried plasma from 120 subjects: 32 CRC patients, 37 IBD patients, 20 DD patients, and 31 healthy controls.

View Article and Find Full Text PDF

Key Clinical Message: Closed-loop bowel obstruction and contained perforation secondary to acute on chronic jejunal diverticulitis is rare and should be included in the differential diagnosis of acute abdomen. The association between polymyalgia rheumatica and diverticular disease requires further research but may prompt clinicians to consider appropriate therapies in patients with both diseases.

Abstract: Jejunal diverticulosis is a sac-like outpouching of the intestinal wall that can cause complications such as diverticulitis, obstruction, abscess, perforation, or fistula formation.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!