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O-Mediated Cu-Catalyzed Dehydrogenative Phenothiazination. | LitMetric

O-Mediated Cu-Catalyzed Dehydrogenative Phenothiazination.

J Org Chem

Institute of Organic Chemistry, RWTH Aachen University, 52074 Aachen, Germany.

Published: January 2025

In contrast to what one can be led to believe upon inspecting some of the recent literature, the dehydrogenative phenothiazination reaction does not require onerous technologies, complicated setups, or advanced catalysts in order to be mild and sustainable. We demonstrate this herein with a most facile, cost-effective, and sustainable Cu(II) catalyzed method, under 1 atm of O at room temperature in methanol, providing broad scope and high yields. These new results further set the dehydrogenative phenothiazination reaction among the green and practical coupling concepts of chemistry.

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Source
http://dx.doi.org/10.1021/acs.joc.4c02590DOI Listing

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