AI Article Synopsis
- Ventriculoperitoneal shunts (VPSs) are essential for treating certain medical conditions, but they come with complications, particularly in light of increasing antibiotic resistance.
- A case was presented involving a serious VPS infection caused by bacteria resistant to colistin, which was successfully treated with intraventricular tigecycline, showing no negative side effects.
- The effectiveness of intraventricular tigecycline against colistin-resistant infections is encouraging, but more research is needed to determine proper dosages and establish guidelines for its use.
Article Abstract
Ventriculoperitoneal shunts (VPSs) have been proven to be life-saving procedures, but their complications pose challenges, particularly in this era of rising antibiotic resistance. We report a critically ill case with VPS infection due to colistin-resistant that was treated with intraventricular tigecycline as salvage therapy without adverse events, resulting in microbiologic cure and clinical response. The use of intraventricular tigecycline in the treatment of colistin-resistant appears promising; however, appropriate dosage adjustments and evidence-based recommendations are needed.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11687230 | PMC |
| http://dx.doi.org/10.36519/idcm.2024.384 | DOI Listing |
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