Relationship between exosomes and cancer: formation, diagnosis, and treatment.

Int J Biol Sci

Health Management Center, General Practice Medical Center, West China Hospital, Sichuan University, Chengdu, China.

Published: January 2025

AI Article Synopsis

  • Exosomes are specialized extracellular vesicles with distinct biological characteristics that play a key role as information molecules, biomarkers, and carriers.
  • They have been linked to malignancies, which are a major cause of sickness and death globally, highlighting the potential for improved diagnosis and treatment through better understanding of exosomes.
  • This study reviews recent developments regarding exosomes in the context of tumors and proposes ideas for their application in cancer diagnosis and therapy.

Article Abstract

Exosomes are a member of extracellular vesicles. However, their biological characteristics differ from those of other vesicles, and recently, their powerful functions as information molecules, biomarkers, and carriers have been demonstrated. Malignancies are the leading cause of high morbidity and mortality worldwide. The cure rate of malignancies can be improved by improving early screening rates and therapy. Moreover, a close correlation between exosomes and malignancies has been observed. An in-depth study of exosomes can provide new methods for diagnosing and treating tumors. Therefore, this study aimed to review, sort, and summarize such achievements, and present ideas and opinions on the application of exosomes in tumor treatment.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11667803PMC
http://dx.doi.org/10.7150/ijbs.95763DOI Listing

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