AI Article Synopsis
- Fungal contamination in hospital air can impact the health of staff, patients, and caregivers, with a study in Wuhan revealing that factors like temperature, humidity, and seasonal changes significantly influence fungal concentration rather than disease type or personnel density.
- The analysis showed that airborne fungal particle sizes are normally distributed, with the highest proportions found in specific size ranges, but the median diameter remained below 3.19 μm across different departments in both winter and summer.
- The findings suggest a need for improved filtration efficiency for specific fungal particle sizes and the use of appropriate antifungal treatments and hygiene practices in hospital air management.
Article Abstract
Fungal contamination in the air of hospital wards can affect the health of medical staff, patients, and caregivers. Through systematic analysis of the concentration, types, and particle size distribution characteristics of fungi in the air of wards in Wuhan, China, in 2023, it was found that there was no significant correlation between the concentration of fungi in the air of wards and the disease type and personnel density. The main influencing factors were temperature, humidity, and seasonal changes. The distribution characteristics of fungal particle size in the wards of various departments in winter and summer showed a roughly normal distribution, with the percentage of particle size gradually increasing from stage I to stage III. The proportion from stage III to stage V was generally the highest, while the proportion from stage V to stage VI gradually decreased. There was no significant difference in the median diameter of airborne fungal conidia between different departments in winter and summer, and the median diameter of fungal conidia was less than 3.19 μm. The dominant fungal genus in the wards during winter and summer were basically the same, and there was no significant difference compared to wards in other inpatient buildings. The current study indicates that more attentions should be paid to the increasing of filtration efficiency of fungal conidia particle sized from 1.1~4.7 μm, and appropriate antifungal and sterilization drugs, equipments and methods should be selected in the maintenance of daily hygiene, including the operation and management of the air conditioning systems in the inpatient wards.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.26444/aaem/193292 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The therapeutic role of naringenin nanoparticles on hepatocellular carcinoma.
BMC Pharmacol Toxicol
January 2025
Biochemistry Department, Faculty of Science, Tanta University, Tanta, Egypt.
Background: Naringenin, a flavonoid compound found in citrus fruits, possesses valuable anticancer properties. However, its potential application in cancer treatment is limited by poor bioavailability and pharmacokinetics at tumor sites. To address this, Naringenin nanoparticles (NARNPs) were prepared using the emulsion diffusion technique and their anticancer effects were investigated in HepG2 cells.
View Article and Find Full Text PDFEffects of LinTT1-peptide conjugation on the properties of poly(ethylene glycol)-block-(ε-caprolactone) nanoparticles prepared by the nanoprecipitation method.
Drug Deliv Transl Res
January 2025
Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki, FI-00014, Finland.
Functionalization of polymer nanoparticles (NPs) with targeting peptides is of interest for drug delivery applications to enhance tumor accumulation and penetration. Herein, we evaluated the feasibility of two different methods for the attachment of a tumor-penetrating peptide LinTT1 (AKRGARSTA) to poly(ethylene glycol)-block-poly(ε-caprolactone) (PCL-PEG) NPs: (1) "post-conjugation" onto pre-formed nanoparticles, and (2) "pre-conjugation", the synthesis and purification of peptide-polymer conjugates and subsequent nanoprecipitation of the conjugates diluted with non-functionalized polymers. Conjugation of the labelled peptide via maleimide-thiol chemistry was verified by gel permeation chromatography (GPC) and fluorescence measurements.
View Article and Find Full Text PDFMethod development and validation on RP-HPLC method for estimation of xanthohumol in nanostructured lipid carriers drug delivery systems.
J Chromatogr B Analyt Technol Biomed Life Sci
December 2024
School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India; Faculty of Health, Australian Research Centre in Complementary and Integrative Medicine, University of Technology Sydney, Ultimo, NSW 2007, Australia. Electronic address:
Xanthohumol(Xn) is isolated from female inflorescences of Humulus lupulus. It has been discovered that Xn and its formulation are useful in the treatment of cancer. As this bioactive compound has medicinal importance, hence, a novel, precise, and sensitive HPLC method should be developed.
View Article and Find Full Text PDFUtilizing conductive materials for reducing methane emissions in postharvest paddy rice soil microcosms.
Sci Total Environ
January 2025
Program of Sustainability in Biosystems, Institute of Agrifood Research and Technology (IRTA), Caldes de Montbui, Barcelona, Spain. Electronic address:
Paddy fields are a major anthropogenic source of global methane (CH) emissions, a powerful greenhouse gas (GHG). This study aimed at gaining insights of different organic and inorganic conductive materials (CMs) - biochar, fungal melanin, and magnetite - to mitigate CH emissions, and on their influence on key microbial populations, mimicking the postharvest season throughout the degradation of rice straw in microcosms under anaerobic conditions encompassing postharvest paddy rice soils from the Ebro Delta, Spain. Results showed that fungal melanin was the most effective CM, significantly reducing CH emissions by 29 %, while biochar amendment also reduced emissions by 10 %.
View Article and Find Full Text PDFConstruction and transcriptomic analysis of salinity-induced lipid-rich flocculent microalgae.
J Environ Manage
January 2025
School of Petrochemical Engineering & Environment, Zhejiang Ocean University, Zhoushan, 316000, China; National & Local Joint Engineering Research Center of Harbor Oil & Gas Storage and Transportation Technology, Zhejiang Key Laboratory of Petrochemical Environmental Pollution Control, Zhoushan, 316000, China. Electronic address:
The lack of cost-effective nutrient sources and harvesting methods is currently a major obstacle to the production of sustainable biofuels from microalgae. In this study, Chlorella pyrenoidosa was cultured with saline wastewater in a stirred photobioreactor, and lipid-rich flocculent microalgae particles were successfully constructed. As the influent salinity of the photobioreactor increased from 0% to 3%, the particle size and sedimentation rate of flocculent microalgae particles gradually increased, and the lipid accumulation of microalgae also increased gradually.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!