Generation of a human induced pluripotent stem cell line NTUHi006-A from a polycystic ovarian syndrome patient.

Chia-Eng Wu Hsiang-Po Huang Hong-Nerng Ho Mei-Jou Chen

Stem Cell Res

Department of Obstetrics and Gynecology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan; Livia Shangyu Wan Chair Professor of Obstetrics and Gynecology, National Taiwan University, Taipei, Taiwan Research Center for Cell Therapy and Regeneration Medicine, Taipei Medical University, Taipei, Taiwan. Electronic address:

Published: February 2025

Polycystic ovary syndrome (PCOS) is a common endocrine disorder related to multifactors and genetic polymorphisms. Here, we derived an induced pluripotent stem cell (hiPSC) line NTUHi006-A from a phenotype A (full-blown) PCOS patients with clinical hyperandrogenism, chronic anovulation, and polycystic ovarian morphology on ultrasonography. NTUHi006-A showed stemness, pluripotency and stem cell-like morphology.

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http://dx.doi.org/10.1016/j.scr.2024.103647	DOI Listing

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