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http://dx.doi.org/10.1186/s13244-024-01873-8 | DOI Listing |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11688257 | PMC |
J Stroke Cerebrovasc Dis
January 2025
Department of Neurosurgery, Lenox Hill Hospital/Northwell Health, New York, NY, USA. Electronic address:
Background: The efficacy and safety of P2Y12 inhibitors (P2Y12i) with aspirin in patients with non-cardioembolic ischemic cerebrovascular events remains a topic of ongoing debate. Therefore, we conducted an updated meta-analysis to compare these drugs with aspirin alone.
Methods: We systematically searched PubMed, Embase, and Cochrane Central for randomized controlled trials (RCTs) comparing the two treatment regimens in patients with ischemic cerebrovascular events.
JAMA Netw Open
January 2025
Department of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University Hospital, Aarhus University, Aarhus, Denmark.
Importance: Current evidence of the association between prenatal exposure to glucocorticoids and long-term mental disorders is scarce and has limitations.
Objective: To investigate the association between prenatal exposure to systemic glucocorticoids and mental disorders in offspring at the age of 15 years, comparing exposed vs unexposed offspring born to mothers with the same underlying disease (risk of preterm delivery and autoimmune or inflammatory disorders).
Design, Setting, And Participants: This nationwide population-based cohort study used data from registries in Denmark with follow-up until December 31, 2018.
Alzheimers Dement
December 2024
Brunel University London, London, United Kingdom.
Background: Mild Behavioral Impairment (MBI) describes a spectrum of late-life onset, sustained neuropsychiatric symptoms grouped in five domains: mood/anxiety, apathy, impulse dyscontrol, social inappropriateness and psychosis. MBI is a well-established correlated of incident dementia and is associated with PET amyloid and blood biomarker profiles consistent with early AD however little is known about the trajectory of MBI. This study set out to determine the course of MBI symptoms in a cohort of older adults with and without subjective cognitive complaints (SCC).
View Article and Find Full Text PDFEur Heart J Case Rep
January 2025
Department of Cardiology, Klinik Landstrasse, Juchgasse 25, A-1030 Wien, Austria.
Background: Atrial flutter (AFL) is usually effectively treated by cavotricuspid isthmus (CTI) ablation. If AFL recurs despite ablation, there is risk of progression to atrial fibrillation (AF) and clinicians should consider underlying structural heart diseases. This consideration becomes especially critical when right-heart-chambers are dilated.
View Article and Find Full Text PDFNat Commun
January 2025
Department of Evolutionary Anthropology, University of Vienna, Vienna, Austria.
Caves are primary sites for studying human and animal subsistence patterns and genetic ancestry throughout the Palaeolithic. Iberia served as a critical human and animal refugium in Europe during the Last Glacial Maximum (LGM), 26.5 to 19 thousand years before the present (cal kya).
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