Background/aim: This study evaluated the outcomes of combining submucosal turbinectomy with extensive disruption of the pterygopalatine ganglionic efferent nerve fibers through a minimucosal incision in patients with intractable rhinitis, irrespective of their dependency on the posterior nasal nerve.
Patients And Methods: We describe an endoscopic extended neurectomy procedure performed via a minimucosal pocket. The primary outcome measures included the Total Nasal Symptom Score (TNSS), Visual Analog Scale (VAS) score, and runny nose and nasal obstruction subdomains of the Sino-Nasal Outcome Test-22 (SNOT-22), which were assessed pre-procedure and at 3 and 6 months post-procedure. The secondary outcomes included the incidence of adverse events and medication dependency.
Results: Six patients with rhinitis [66.7% female, 66.7% allergic rhinitis, average age: 48.17 (26-69) years] received treatment and completed a 6-month evaluation, with a mean follow-up period of 16.5 (8-30) months. The modified technique significantly reduced VAS scores from 8.67±1.21 to 0.50±0.55 (p=0.035) and TNSS from 8.83±2.40 to 1.17±0.75 (p=0.031) at three months compared to baseline. These effects were sustained at six months (p=0.0335 and p=0.0355, respectively). The severity and frequency of rhinorrhea and nasal congestion showed marked improvement, as assessed by the TNSS and SNOT-22. None of the patients experienced severe post-procedural adverse events, and all ceased medication use at the last follow-up visit.
Conclusion: Transturbinectomy extended neurectomy based on surgical dissection is a feasible technique and could be considered as a potential alternative to standard treatments for patients with intractable rhinitis.
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http://dx.doi.org/10.21873/invivo.13853 | DOI Listing |
J Orthop Surg Res
January 2025
Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, P. R. China.
Objective: To investigate the application value of arthroscopic channel modification in meniscal injury repair.
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BMC Womens Health
January 2025
Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, UK.
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View Article and Find Full Text PDFBMC Public Health
January 2025
Center for Global Health, Weill Cornell Medicine, 402 East 67 Street, 2 Floor, New York, NY, 10065, USA.
Background: Uncontrolled hypertension is the leading modifiable risk factor for cardiovascular disease mortality and remains high in low-middle income countries like Haiti. Barriers and facilitators to achieving hypertension control in urban Haiti remain poorly understood. Elucidating these factors could lead to development of successful interventions.
View Article and Find Full Text PDFJ Cancer Surviv
January 2025
School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.
Purpose: This study aimed to evaluate the prevalence and predictors of frailty and the association between frailty and neurocognitive impairments among Chinese survivors of childhood cancer.
Methods: A total of 185 survivors of childhood cancer were recruited from a long-term follow-up clinic in Hong Kong (response rate: 94.4%; 48.
Pediatr Res
January 2025
Center for Genetic Medicine, Children's National Research Institute, Washington, DC, USA.
Background: Prenatally transmitted viruses can cause severe damage to the developing brain. There is unexplained variability in prenatal brain injury and postnatal neurodevelopmental outcomes, suggesting disease modifiers. Of note, prenatal Zika infection can cause a spectrum of neurodevelopmental disorders, including congenital Zika syndrome.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!