AI Article Synopsis
- The two-step cancer screening method uses OncoSeek and SeekInCare to effectively reduce false positives while identifying cancer cases.
- The first test, OncoSeek, leads to a significantly high number of false positives at 441,450, but when combined with SeekInCare, this drops to just 34,335.
- Compared to other tests, the two-step approach is much more cost-effective, costing only $713.6 million versus $3,750 million for SeekInCare and $4,745 million for Galleri.
Article Abstract
Large-scale screening inevitably leads to significant financial burdens on the healthcare system, which is a key factor constraining nationwide screenings. The two-step MCED approach not only maintains comparable performance but also substantially alleviates financial strains compared with the direct use of next-generation sequencing-based MCED tests for massive screenings.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758400 | PMC |
| http://dx.doi.org/10.1158/2767-9764.CRC-24-0508 | DOI Listing |
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