Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/qjmed/hcae248 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Correlation of physicochemical properties with antioxidant activity in phenol and thiophenol analogues.
Sci Rep
January 2025
Department of Chemistry, University of Massachusetts Boston, 100 Morrissey Blvd, Boston, MA, 02125, USA.
Oxidative stress, associated with excessive production of reactive oxygen and nitrogen species (ROS, RNS), contributes to the development and progression of many ailments, such as aging, cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, cancer, preeclampsia or multiple sclerosis. While phenols and polyphenols are the most studied antioxidants structurally similar compounds such as anilines or thiophenols are sporadically analyzed despite their radical scavenging potential. This work assesses the impact of structural features of phenols and thiophenols on their antioxidant activity.
View Article and Find Full Text PDFEtiological and clinical characterization of longitudinally extensive spinal cord lesions: A 12-year tertiary center experience.
Mult Scler Relat Disord
December 2024
Department of Neurology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Introduction: Longitudinally extensive spinal cord lesions (LESCL) are characterized by T2-hyperintense signals spanning at least three vertebral body segments, with neuromyelitis optica spectrum disorders (NMOSD) being a significant cause. This study aimed to characterize the clinical, radiological, serological, and cerebrospinal fluid (CSF) features of LESCL and to compare NMOSD and non-NMOSD cases.
Methods: We conducted a retrospective cross-sectional study of adult patients diagnosed with LESCL at our center over a twelve-year period collecting data on demographics, clinical presentations, MRI findings, CSF analysis, and serological testing for AQP4-IgG and MOG-IgG antibodies.
Extensive Sclerotic Skin Involvement in Erdheim-Chester Disease.
QJM
December 2024
Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College.
The epidemiologic trend of multiple sclerosis in Razavi Khorasan Province, Iran in fifteen-year period.
Mult Scler Relat Disord
December 2024
Department of Radiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Objective: Multiple sclerosis (MS) is a major global health problem as a growing debilitating disease and according to the Global Burden of Diseases study in 2016 has had a 40 % prevalence increase in Iran during the 3 previous decades; far more from the Global prevalence which only increased about 10 %. Razavi Khorasan is the second most populous province in Iran with over 6.5 million people and its MS status is not clear; therefore, this study aims to define the current epidemiologic trend of MS in Razavi Khorasan METHODS AND MATERIALS: We performed this cross-sectional, analytical study in Khorasan Razavi Multiple sclerosis Center during 2021-2023.
View Article and Find Full Text PDFProtective role of Angiogenin in muscle regeneration in amyotrophic lateral sclerosis: Diagnostic and therapeutic implications.
Brain Pathol
December 2024
Laboratory of Neurobiology and Molecular Therapeutics, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy.
Amyotrophic lateral sclerosis (ALS) is a fatal neuromuscular disease with no effective treatments, in part caused by variations in progression and the absence of biomarkers. Mice carrying the SOD1G93A transgene with different genetic backgrounds show variable disease rates, reflecting the diversity of patients. While extensive research has been done on the involvement of the central nervous system, the role of skeletal muscle remains underexplored.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!