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Adaptive Multi-Kernel Graph Neural Network for Drug-Drug Interaction Prediction.
Interdiscip Sci
January 2025
School of Computer Science, Qufu Normal University, Rizhao, 276826, China.
Combination therapy, which synergistically enhances treatment efficacy and inhibits disease progression through the combined effects of multiple drugs, has emerged as a mainstream approach for treating complex diseases and alleviating symptoms. However, drug-drug interactions (DDIs) can sometimes lead to adverse reactions, potentially endangering lives. Therefore, developing efficient and accurate DDI prediction methods is crucial for elucidating drug mechanisms and preventing side effects.
View Article and Find Full Text PDFUsing Social Media to Promote Life Skills Among Adolescents: A Debate on Opportunities, Challenges, and Implications for Health and Education.
J Prev (2022)
January 2025
Department of Health and Prevention, Institute of Psychology, University of Greifswald, Robert-Blum-Str. 13, 17489, Greifswald, Germany.
The digitalization of society increasingly blurs boundaries between analog and digital worlds, offering opportunities such as telemedicine and global connectivity through digital platforms. However, it also presents risks, including cyberbullying, addiction potential, harmful content, misinformation, and privacy concerns from data breaches and surveillance technologies. Social media, with its global reach, amplifies both opportunities for positive engagement and the responsibility to navigate largely unregulated content.
View Article and Find Full Text PDFWorkplace Ergonomic Adjustments and Supportive Policies During the Pregnancy of a Paint Sprayer: A Case Report.
Cureus
December 2024
Faculty of Medical Sciences, The University of the West Indies, St. Augustine, TTO.
A 29-year-old paint sprayer presented with mild lower back pain and fatigue related to prolonged standing and repetitive tasks in the first few weeks of pregnancy. An initial assessment included a review of her workstation, evaluation of posture, and standard prenatal tests such as routine blood work and ultrasound. These investigations showed normal fetal development and no complications.
View Article and Find Full Text PDFUnderstanding the Impacts of Surgical Drains on Postoperative Pain and Quality of Life.
Plast Reconstr Surg Glob Open
January 2025
Division of Plastic and Reconstructive Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA.
Background: Surgical drains are commonly used in breast surgery and breast reconstruction for seroma prevention. Although many surgeons are aware that surgical drains can cause considerable discomfort to patients, less is understood about the specific impacts of drains on postoperative pain and quality of life (QOL).
Methods: A cross-sectional survey was conducted among patients at our institution who had previously undergone mastectomy or breast reconstruction procedures to better understand patients' experiences with surgical drains.
The clinical application of artificial intelligence in cancer precision treatment.
J Transl Med
January 2025
Department of General Surgery & Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy / Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Background: Artificial intelligence has made significant contributions to oncology through the availability of high-dimensional datasets and advances in computing and deep learning. Cancer precision medicine aims to optimize therapeutic outcomes and reduce side effects for individual cancer patients. However, a comprehensive review describing the impact of artificial intelligence on cancer precision medicine is lacking.
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