Background: Virtual surgical planning (VSP) is an emerging method in head and neck reconstruction with demonstrated benefits, however, its economic viability is supported with mixed evidence.
Methods: A structured search was performed in five electronic databases. Studies that performed an economic evaluation on VSP in head and neck reconstruction were included. Data regarding VSP workflow, costs, and variables influencing costs were recorded and synthesized.
Results: Eighteen studies met the final inclusion criteria (n = 733). Fourteen out of 18 studies (78%) found that VSP either generated cost savings or was comparable to freehand surgery (FHS). The majority of cost savings were generated from reduced OR times and LOS/LOH. In addition, greater cost savings were associated with in-house VSP workflows compared to those that are outsourced.
Conclusion: VSP is potentially cost-beneficial compared to traditional unplanned surgery, however, substantial heterogeneity amongst methods and outcome measures impedes the generalizability of these findings.
Trial Registration: PROSPERO: CRD42024504398.
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