In this paper, compact terahertz (THz) metachips for hyperspectral screening and quantitative evaluation of human cancer cells is reported. This pixelated resonant metachips feature the resonance channel from 1 and 3 THz frequency with a record-high quality factor (up to 230). Through the interactions of various cancer cells of different concentrations, high-dimensional spectral signatures are obtained, which are further transformed into a spatial map for labelling and quantification purposes. The screening of up to 15 cancer cells is experimentally reported, with very high detecting accuracy of 93.33% and with attractive quantitative concentration sensitivity up to 1320 kHz cell mL. This hyperspectral metachips are low-cost, highly compact, and label-free for fast, high-throughput and high-sensitivity detections and evaluation of human cancer cells. This technology does not require clinical experience, representing an accessible technology for early diagnosis of cancer.
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| http://dx.doi.org/10.1002/adma.202412738 | DOI Listing |
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