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Mycobacterium tuberculosis in hepatic hilum as a cause of erythema induratum of Bazin.
Diagn Microbiol Infect Dis
December 2024
Servicio de microbiología del Hospital, Universitario Nuestra Señora, de la Candelaria, Tenerife, España.
Erythema induratum of Bazin (EIB) is a rare manifestation of cutaneous tuberculosis, typically associated with active tuberculosis infections. We present the case of a 75-year-old immunocompetent Spanish woman who developed nodular lesions on her lower limbs. Initial differential diagnoses included sporotrichosis, erythema nodosum, Sweet's syndrome, sarcoidosis, and tuberculosis.
View Article and Find Full Text PDFA case report: Endobronchial ultrasound guided biopsy of radiographically normal size thoracic lymph nodes supporting diagnosis of cardiac sarcoidosis.
Respir Med Case Rep
November 2024
Department of Pulmonary and Critical Care Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH, USA.
Sarcoidosis is a rare chronic granulomatous disease with unknown etiology. Definite diagnosis of cardiac sarcoidosis (CS) is especially difficult to establish. Several guidelines exist to make a diagnosis of CS but those have not been clinically validated.
View Article and Find Full Text PDFMore evidence that sarcoidosis is a host disease, and the identity of the aetiological triggers is irrelevant.
Eur Respir J
December 2024
Department of Pulmonary and Critical Care Medicine, Integrated Hospital Care Institute, Cleveland Clinic, Cleveland, OH, USA.
Trident Sign: The Key Magnetic Resonance Imaging Finding Distinguishing Spinal Cord Sarcoidosis From Multiple Sclerosis and Seropositive Neuromyelitis Optica Spectrum Disorder.
Ochsner J
January 2024
The University of Queensland Medical School, Ochsner Clinical School, New Orleans, LA.
Spinal cord sarcoidosis, an uncommon manifestation of neurosarcoidosis, presents diagnostic and therapeutic challenges because the condition is rare and has diverse clinical manifestations that can mimic other conditions such as multiple sclerosis and neuromyelitis optica spectrum disorder. A middle-aged African American female with a history of idiopathic intracranial hypertension and hydrocephalus with ventriculoperitoneal shunt presented with progressive, predominantly left-sided gait instability, weakness, and paresthesia. Cerebrospinal fluid showed lymphocytosis, red blood cells, elevated oligoclonal bands, and elevated kappa free light chains, concerning for multiple sclerosis.
View Article and Find Full Text PDFThe predictive effects of adiponectin and irisin hormones on diagnosis and clinical involvement of Sarcoidosis.
BMC Pulm Med
December 2024
Department of Biochemistry, University of Kocaeli, Kocaeli, Turkey.
Background: Sarcoidosis is a chronic disease of unknown etiology characterised by systemic non-caseating granulomas that can affect any organ in the body, especially the lungs and in which genetic and environmental factors are thought to play a role in its pathophysiology. Adipokines and myokines secreted from adipose and muscle tissue play a role in the pathogenesis or protection against many inflammatory and autoimmune diseases in which inflammation and immunity form the basis. In our study, we aimed to investigate the role of the irisin and adiponectin in sarcoidosis.
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