The Neurophysiological Impact of Touch-Based Therapy: Insights and Clinical Benefits.

The evidence on how touch-based therapy acts on the brain activity opens novel cues for the treatment of chronic pain conditions for which no definitive treatment exists. Touch-based therapies, particularly those involving C-tactile (CT)-optimal touch, have gained increasing attention for their potential in modulating pain perception and improving psychological well-being. While previous studies have focused on the biomechanical effects of manual therapy, recent research has shifted towards understanding the neurophysiological mechanisms underlying these interventions. CT-optimal touch, characterized by gentle stroking that activates CT afferents, may be used to reduce pain perception in chronic pain conditions and to enhance psychological well-being. Further research is needed to fully elucidate the neurophysiological mechanisms involved and to establish the therapeutic efficacy of CT-optimal touch in various clinical populations.