Osteoblastoma is a benign disease usually treated with complete resection with curative intent, and it accounts for 14% of the benign bone tumors. A more uncommon presentation refers to a rapid growing mass known as aggressive osteoblastoma. We report the case of a young male with cervical swelling due to a progressive mass on the right side of neck with 3 months of evolution. Incisional biopsy demonstrated grade 3 osteoblastoma. A radical surgical resection was attempted, but complete resection was not feasible because of cervical invasion of C3 without spinal involvement. Despite the lack of robust data, intensity modulated radiotherapy was performed in the ipsilateral cervical region at a dose of 50 Gy in 25 fractions until November 2013. The patient is being followed up regularly without evidence of recurrence since. The so far successful treatment highlights the importance of a multidisciplinary approach for treating patients with aggressive osteoblastoma.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11679614 | PMC |
http://dx.doi.org/10.1055/s-0041-1739300 | DOI Listing |
Genes Chromosomes Cancer
November 2024
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Conventional high-grade osteosarcomas are characterized by aggressive radiologic features, cytologic pleomorphism, and complex genomics. However, rare examples of osteosarcomas remain challenging due to unusual histology, such as sclerosing or osteoblastoma-like features, which may require molecular confirmation of their complex genetic alterations. We have encountered such a case in a 17-year-old man, who presented with a third metatarsal sclerotic bone lesion, found incidentally in the work-up of a foot trauma.
View Article and Find Full Text PDFJ Neurosurg Case Lessons
November 2024
Department of Neurosurgery, The University of Texas Medical Branch at Galveston, Texas.
Background: Aneurysmal bone cysts (ABCs) are rare, benign, yet locally aggressive lesions that contain blood-filled channels that rarely occur in the thoracic spine of adults. The literature on the treatment of spinal ABCs is sparse, but the consensus is to achieve gross-total resection (GTR) due to these lesions being locally aggressive and to prevent recurrence.
Observations: This report describes a 35-year-old female admitted with back pain and right T5 dermatome radiculopathy without any inciting events.
J Craniomaxillofac Surg
January 2025
Division of Head and Neck Surgery, Department of Oral and Maxillofacial Surgery, University of Florida College of Medicine, Jacksonville, Florida, USA.
Epithelioid osteoblastoma (EOB) is a rare, benign bone tumor characterized by the proliferation of atypical epithelioid osteoblasts within a vascular stroma. It typically presents as a slow-growing painful mass and requires careful differentiation from more aggressive lesions like osteosarcoma for appropriate management. We present a case of an otherwise healthy 30-year-old man who presented with a mandibular EOB measuring 23 cm × 17 cm x 19 cm, causing significant disfigurement and functional impairment.
View Article and Find Full Text PDFSurg Neurol Int
January 2024
Department of Neurosurgery, Kocaeli University, School of Medicine, Kocaeli, Turkey.
Background: Osteoblastomas, although rare, are benign primary bone tumors, with cervical spine involvement being exceptionally uncommon. Late diagnosis, especially in aggressive cases, can lead to surgical challenges. Oxidized regenerated cellulose (ORC) used for hemostasis may result in complications if left in the surgical field.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!