Objective: Transcarotid artery revascularization (TCAR) is a safe minimally invasive option for patients with carotid artery stenosis who are not appropriate candidates for carotid endarterectomy (CEA). Many physicians have not yet adopted this technique in the management of carotid artery stenosis. The aim of this study is to explore overall outcomes of carotid revascularization based on physicians' practices in the Vascular Quality Initiative (VQI).
Methods: Individual physicians participating in both the carotid artery stenting (CAS) and carotid endarterectomy (CEA) modules in VQI were categorized as performing CEA and TCAR, CEA and transfemoral carotid artery stenting (TFCAS), or all three procedures (CEA, TCAR, and TFCAS). Physicians performing CEA only or TCAR/TFCAS only were excluded. In-hospital and 1-year outcomes were compared between the three groups using univariable and multivariable analysis.
Results: A total of 104,925 carotid revascularization procedures performed by 1433 physicians were included. Most physicians performed CEA and TCAR (n = 714; 49.8%), whereas 35.1% (n = 503) performed all three procedures, and 15.1% (n = 216) performed CEA and TFCAS only. Physicians performing CEA and TFCAS had higher overall stroke/death rates after carotid procedures (2.2%) compared with those performing CEA and TCAR (1.4%) or those performing all three procedures (1.6%; P < .001). They also had higher rates of cranial nerve injuries (3.1% vs 1.9% vs 1.9%; P < .001). After adjusting for baseline characteristics, procedures performed by CEA and TFCAS physicians had significantly higher odds of in-hospital stroke/death compared with those in the CEA and TCAR group (odds ratio, 1.31; 95% confidence interval [CI], 1.03-1.66; P = .03). They also had increased hazard of 1-year stroke/death (hazard ratio, 1.45; 95% CI, 1.1-1.9; P = .01). No significant difference in the adjusted odds of stroke/death was observed between CEA and TCAR performers vs CEA, TCAR, and TFCAS performers (odds ratio, 1.05; 95% CI, 0.92-1.20; P = .44). When adjusting for the type of carotid revascularization technique, difference in outcomes based on surgeon's experience were no longer significant, indicating that differences in outcomes were procedure-specific and attributable to the inferior outcomes associated with TFCAS compared with CEA and TCAR. TCAR case volumes did not impact outcomes of carotid revascularization. On the other hand, a high TFCAS volume among physicians performing all three carotid procedures was associated with higher overall in-hospital and 1-year mortality.
Conclusions: Physicians' preference for carotid artery stenosis management has a bearing on their overall stroke/death rates. Careful patient and procedure selection are the cornerstone to improve carotid revascularization outcomes.
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http://dx.doi.org/10.1016/j.jvs.2024.12.125 | DOI Listing |
Ann Vasc Surg
January 2025
Division of Vascular and Endovascular Surgery, Mayo Clinic, Jacksonville, FL. Electronic address:
Introduction: Carotid artery stenosis is a significant contributor to ischemic strokes, and its surgical management includes carotid artery endarterectomy (CEA), transfemoral carotid artery stenting (TF-CAS), and trans carotid artery revascularization (TCAR). CEA has traditionally been preferred, but TF-CAS and TCAR are also excellent alternative options if the anatomy of the vessels allows them. This study reports our short- and mid-term outcomes after carotid artery revascularization in symptomatic patients at a stroke center.
View Article and Find Full Text PDFJ Vasc Surg
December 2024
Division of Vascular Surgery, Indiana University School of Medicine, Indianapolis, IN.
Objective: Transcarotid artery revascularization (TCAR) is a safe minimally invasive option for patients with carotid artery stenosis who are not appropriate candidates for carotid endarterectomy (CEA). Many physicians have not yet adopted this technique in the management of carotid artery stenosis. The aim of this study is to explore overall outcomes of carotid revascularization based on physicians' practices in the Vascular Quality Initiative (VQI).
View Article and Find Full Text PDFJ Vasc Surg Cases Innov Tech
February 2025
Division of Vascular Surgery, Department of Cardiothoracic and Vascular Surgery, McGovern Medical School at UTHealth Houston, Houston, TX.
Persistent hypoglossal artery (PHA) is a rare, anatomical variant in which the posterior cerebral circulation is primarily supplied by a branch of the carotid artery, rather than the vertebral arteries. This case report discusses carotid endarterectomy performed on a man, 67 years of age, with high-grade, asymptomatic carotid artery stenosis and ipsilateral PHA. Preoperative computed tomography angiography identified the PHA arising from the internal carotid artery, compensating for atretic bilateral vertebral arteries and providing primary perfusion to anterior spinal artery.
View Article and Find Full Text PDFJ Cardiovasc Surg (Torino)
October 2024
University of California, Davis Medical Center, Sacramento, CA, USA -
Transcarotid artery revascularization (TCAR) is a hybrid approach with neuroprotective flow reversal for treating carotid stenosis. Providers are increasingly choosing it for patients, especially those at high risk for carotid endarterectomy (CEA). However, TCAR's efficacy is limited by calcific atherosclerosis, which can hinder stent expansion and increase the risk of perioperative embolization.
View Article and Find Full Text PDFAnn Vasc Surg
January 2025
Division of Vascular Surgery, Beth Israel Deaconess Medical Center, Harvard University, Boston, MA.
Background: Transcarotid artery revascularization (TCAR) has emerged as an alternative therapeutic modality to carotid endarterectomy (CEA) and transfemoral carotid artery stenting (TFCAS) for the management of patients with carotid artery stenosis. However, certain issues regarding the indications and contraindications of TCAR remain unanswered or unresolved. The aim of this international, expert-based Delphi consensus document was to attempt to provide some guidance on these topics.
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