Silent circulation of plasmid-borne tet(X6) and bla genes in a community-acquired Acinetobacter baumannii strain.

Drug Resist Updat

Department of Clinical Laboratory, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China; Key Laboratory of Precision Medicine in Diagnosis and Monitoring Research of Zhejiang Province, Hangzhou, China. Electronic address:

Published: December 2024

To characterize the genomic features of a community-acquired Acinetobacter baumannii strain, co-carrying tet(X6) and bla genes, but was susceptible to tigecycline and carbapenems. The tet(X6) and bla genes were found on a 149,518 bp non-conjugative plasmid. The bla gene was silent, due to the presence of an intact ISAba3-like element upstream, which rendered the strain susceptible to carbapenems.

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http://dx.doi.org/10.1016/j.drup.2024.101194DOI Listing

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