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Comment on "Tonic stretch reflex threshold as a measure of disordered motor control and spasticity - A critical review" by Levin et al. (2024).
Clin Neurophysiol
December 2024
Center for Neuroscience and Neurological Recovery, Methodist Rehabilitation Center, Jackson, MS, USA.
To Ib or not to b: Transcriptional regulation of tonic type Ib vs. phasic type Is motor neurons.
Neuron
November 2023
Department of Neuroscience, Brown University, Providence, RI, USA; Carney Institute for Brain Science, Brown University, Providence, RI, USA. Electronic address:
Neuronal diversity is a hallmark of the nervous system that has captivated scientists for over a century. In this issue of Neuron, Suresh Jetti and colleagues report the identification of genes that differentiate two closely related but functionally distinct Drosophila neurons through single-cell Patch-seq..
View Article and Find Full Text PDFThe neurocircuitry of fasting-induced glucocorticoid release.
Cell Metab
September 2023
Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.
Activation of the hypothalamus-pituitary-adrenal gland (HPA) axis confers adaptations to homeostatic perturbations including food scarcity. A comprehensive new study by Douglass et al. disentangled how agouti-related peptide (AgRP)-expressing neurons of the arcuate nucleus (ARC) trigger rapid HPA-axis activation in response to fasting, which is mediated by repression of a tonic, inhibitory neuro circuit.
View Article and Find Full Text PDFCan tonic motor activation be the magical elixir for restless legs syndrome?
Sleep
October 2023
Department of Neurology, Yale University, New Haven, CT, USA.
Treatment of chronic cluster headache with burst and tonic occipital nerve stimulation: A case series.
Headache
September 2023
Department of Neurosurgery, Aarhus University Hospital, Aarhus, Denmark.
Objectives And Background: Chronic cluster headache (CCH) is a rare but severely debilitating primary headache condition. A growing amount of evidence suggests that occipital nerve stimulation (ONS) can offer effective treatment in patients with severe CCH for whom conventional medical therapy does not have a sufficient effect. The paresthesia evoked by conventional (tonic) stimulation can be bothersome and may thus limit therapy.
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