Introduction And Importance: Dilation and stretching of the collecting system of the kidney due to obstruction of urine flow is called hydronephrosis. This case may be accompanied by the presence of pus known as pyonephrosis. This case report reporting massive pyonephrosis in pediatrics related to management and source of control.
Case Presentation: A 10-year-old boy came in with the main complaints of high fever, decreased appetite, vomiting, and nausea. The examination showed left severe hydronephrosis (+) with a size of 14.59 × 6.9 × 9.2 cm. The patient underwent percutaneous nephrostomy (PCN) and showed pus production. From the antegrade pyelography (APG) during PCN, it was stenosis of the left ureteropelvic junction (UPJ). Empirical antibiotics were administered, followed by albumin transfusion. Antibiotics were changed on day 3 post-PCN when urine culture results showed Staphylococcus aureus. After successful improvement of the general condition and minimal pus production from PCN, the patient had a Double J Stent (DJ) and pyeloplasty on the left UPJ. The patient was discharged on day 4 after the left pyeloplasty.
Clinical Discussion: Management of UPJ Stenosis with massive hydronephrosis complications can be done in two stages with the first stage being the diversion of pus from the kidney, then followed by pyeloplasty management. Management is continued with nephrostomy or ureteral stent placement for urine diversion. Management of bacterial infections is adjusted according to culture results.
Conclusion: Management of hydronephrosis with pyonephrosis as complications can be be carried out in two stages, pus diversion, then followed by the pyeloplasty.
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http://dx.doi.org/10.1016/j.ijscr.2024.110766 | DOI Listing |
Multimed Man Cardiothorac Surg
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• Pediatric and Congenital Cardiac Surgery, LMU University Hospital, Munich, Germany • Congenital Cardiac Surgery, German Heart Center Munich, Munich, Germany • European Pediatric Heart Center EKHZ Munich, Munich, Germany.
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View Article and Find Full Text PDFNeurocase
January 2025
Department of Radiology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Catatonia may manifest as an independent entity or as a feature of a neuropsychiatric or medical illness. While electroconvulsive therapy (ECT) is the gold standard treatment for catatonia, it is typically administered if the patient's symptoms fail to respond to benzodiazepines. We describe the case of a 22-year-old male with Budd Chiari induced cirrhosis and no prior psychiatric history, who presented with symptoms of psychosis and hepatic encephalopathy, was treated in the ICU for multi-factorial delirium, developed symptoms of catatonia that failed to respond to lorazepam, ultimately requiring ECT with a favorable response.
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Department of Head & Neck Surgery, Singapore General Hospital, Singapore, Republic of Singapore.
The cases of head and neck cancer among persons with intellectual disability (PWID) are infrequently reported and therefore poorly understood. PWID often face increased barriers of access to healthcare, which can be further compounded when faced with a cancer diagnosis. This report presents the case of a 34-year-old Chinese female patient with Rett syndrome and intellectual disability, presenting with two primary cancers of the tongue and the trachea.
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Department of Pediatric and Preventive Dentistry, Centre for Dental Education and Research, AIIMS, New Delhi, India.
Renal tubular acidosis (RTA) is a group of disorders in which there is an alteration in acid-base homeostasis because of the impairment of nephrons to excrete hydrogen ions or reabsorb bicarbonate ions, resulting in chronic metabolic acidosis. RTA is an important cause of rickets, particularly 'resistant rickets'. Dental manifestations frequently reported in patients with RTA include enamel hypoplasia and amelogenesis imperfecta, affecting permanent dentition.
View Article and Find Full Text PDFMol Genet Genomic Med
January 2025
Diagnostics and Therapeutics of Intractable Diseases, Intractable Disease Research Center, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Background: Sengers syndrome is an autosomal recessive mitochondrial DNA depletion syndrome characterized by hypertrophic cardiomyopathy, congenital cataracts, skeletal myopathy, exercise intolerance, and lactic acidosis. Dysfunction of acylglycerol kinase (AGK) is responsible for the disease, and several AGK gene variants have been reported.
Methods: We employed a comprehensive genomic analysis approach, including whole-genome sequencing and RNA sequencing, combined with various bioinformatics tools.
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