Cellulite is an aesthetically distressing skin condition occurring in 80-90% of females and manifesting as dimples and depressions, producing an uneven surface to the skin. Our aim was to evaluate the effect of combined oral consumption of two dietary supplements based on chokeberry and tart cherry juices over a period of 32 days on cellulite reduction. Twenty women aged 21-49 with a cellulite grade of 1-2 according to the Nurnberger-Muller scale were participating in the study. Ultrasonography was applied to analyze the skin structure in addition to biochemical and anthropometric parameters, which were measured before starting the treatment and after 32 days. A reduction in the thickness of the dermis with subcutaneous fat tissue, subcutaneous fat tissue alone, epidermis, and dermis with epidermis (15.02, 14.34, 21.98, and 20.94%, respectively) was noticed, while the length of the fascicles was reduced by 35.93%. Out of 20 subjects, 11 (57.9%) had edema of the dermis at the beginning of the study, which was not recorded at the end of the study. Moreover, a statistically significant increase in the tissue doppler (TD) signals was recorded in all subjects treated with two dietary supplements, indicating a better blood supply. Changes in anthropometric and biochemical parameters were not recorded. Creatinine, urea, ALT, and AST values, as indicators of kidney and liver function, remained at normal reference levels, pointing out the product's safety. The positive effect of chokeberry and tart cherry juice-based dietary supplements consumption in cellulite condition could be connected with microcirculation improvements.
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http://dx.doi.org/10.1007/s11130-024-01261-z | DOI Listing |
Sci Rep
December 2024
Department of Nephrology, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, 750004, China.
The gut microbiota alterations interact with the pathogenesis and progression of chronic kidney disease (CKD). Probiotics have received wide attention as a potential management in CKD. We investigated the effects of Lactobacillus paracasei N1115 (LP N1115) on intestinal microbiota and related short-chain fatty acids (SCFAs) in end stage kidney disease patients on peritoneal dialysis (PD) in a single-center, prospective, randomized, double-blind, placebo-controlled study.
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December 2024
Department of Animal Sciences, College of Agriculture, Isfahan University of Technology, Isfahan, Iran.
The objective of this research was to examine the impact of feeding biologically treated rumen digesta (BTRD) to Holstein steer calves at levels of 0, 10, 20, and 30% (DM-based) on feed consumption, nutrient digestion, growth performance, rumen fermentation, and plasma metabolites. Sixteen Holstein steer calves with an initial BW of 113 ± 8 kg were randomly allocated in a randomized complete design. Dietary inclusion of BTRD in calves diet did not altered (P < 0.
View Article and Find Full Text PDFBMC Microbiol
December 2024
Departments of Geriatrics, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, P. R. China.
Background: Evidence has revealed that oestrogen deprivation-induced osteolysis is microbiota-dependent and can be treated by probiotics. However, the underlying mechanism require further investigation. This study aims to provide additional evidence supporting the use of probiotics as an adjuvant treatment and to explore the pathophysiology of oestrogen-deprived osteolysis.
View Article and Find Full Text PDFBMC Pregnancy Childbirth
December 2024
Department of Public Health, College of Medicine and Health Sciences, Samara University, Samara, Ethiopia.
Background: Despite the integration of iron supplementation into routine antenatal care programs as a nutritional intervention to prevent anemia in pregnant women, the use of this supplement for the recommended duration remains low in sub-Saharan Africa (SSA). Evidence on maternal compliance with iron supplementation at the SSA level is lacking and most of the previous studies have been limited to specific geographic areas. Therefore, the current study used large population survey data from 35 SSA countries to estimate the pooled prevalence of non-adherence and its determinants.
View Article and Find Full Text PDFBone
December 2024
Neurobehavioral Pharmacology Laboratory, Department of Pharmacology, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India. Electronic address:
Medium chained triglycerides (MCT) ketogenic diet is being extensively investigated for its neuroprotective effects against adverse effects associated with aging and neurodegenerative disorders. Aging is a common risk factor for the development of both osteoporosis and neurological disorders. Hence, suppression of aging and age-related neurodegeneration might contribute to delaying skeletal aging.
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