This study evaluated the cytotoxicity and biocompatibility of a new strontium silicate-based root canal sealer (C-Root SP), in comparison with those of iRoot SP and AH plus. The sealer extract was diluted to the concentrations of 100%, 75%, 50%, and 25%. L929 cells were cultured for 24 h, and the absorbance value was determined. Two-way analysis of variance (two-way ANOVA) and sealers were implanted in the tibia of Sprague-Dawley (SD) rats, At 2, 6, and 12 weeks, rats were euthanised. The tissue reaction was evaluated by HE staining. The least significant difference (LSD) t-test and Kruskal-Wallis test were used. The cytotoxicity of C-Root SP and iRoot SP was found to be less than that of AH plus. At 12 weeks, new bone formation was induced around C-Root SP and iRoot SP sealer, but minimal evidence of bone formation was found in AH plus. C-Root SP has low cytotoxicity and superior biocompatibility.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/aej.12916 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Evaluation of dentists' clinical practices and antibiotic use in managing endodontic emergencies in Karachi, Pakistan: a cross-sectional survey.
BMC Oral Health
December 2024
Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.
Background: Endodontic emergencies, often presented as acute pain or swelling, constitute a substantial challenge in dental practice. While effective management emphasizes prompt intervention, antibiotics are typically indicated only when systemic signs and symptoms are present. There is limited research exists on evaluating the knowledge and clinical approach of dental practitioners in managing endodontic emergencies from our region of the world.
View Article and Find Full Text PDFCytotoxicity and Bone Biocompatibility of the C-Root SP Experimental Root Canal Sealer.
Aust Endod J
December 2024
Department of Oral, College of Stomatology, North China University of Science and Technology, Tangshan City, Hebei Province, People's Republic of China.
This study evaluated the cytotoxicity and biocompatibility of a new strontium silicate-based root canal sealer (C-Root SP), in comparison with those of iRoot SP and AH plus. The sealer extract was diluted to the concentrations of 100%, 75%, 50%, and 25%. L929 cells were cultured for 24 h, and the absorbance value was determined.
View Article and Find Full Text PDFUnveiling the mechanical performance of partially replaced coronal restorations in root canal-treated teeth: an in-vitro study.
BMC Oral Health
December 2024
Department of Conservative Dentistry, Faculty of Dentistry, Minia University, Minia, Egypt.
Objectives: To compare the mechanical performance of partially replaced (repaired) intra-coronal restorations to totally replaced ones in root canal-treated teeth.
Methods: Thirty maxillary second premolars were selected according to strict criteria, mounted on moulds, and had mesio-occluso-distal (MOD) cavities prepared. Resin composite restorative material was used to perform the initial restoration, followed by aging procedures using thermo-mechanical cycling fatigue to replicate six months of intraoral aging.
Vertical root fractures and cracked teeth: post-endodontic root dentinal status through micro-CT assessment after ex vivo fiber post removal.
Clin Oral Investig
December 2024
Departament of Clinic Dentistry, UFF- Universidade Federal Fluminense, Niterói, RJ, Brazil.
Objectives: This study aimed to investigate cracked teeth and vertical root fracture observable on micro-CT images of extracted roots of mandibular incisors, after fiber post removal.
Materials And Methods: Thirty mandibular incisors were selected with any degree of slight incisal wear inspected with the aid of a stereomicroscope under 12x magnification, in order to have a group of young adult specimens according to the criteria of Hugoson et al. A sample of twelve mandibular incisors were selected, aged between 20 and 30 years old, with similar dentine volume and thickness.
The Grotte du Bison Neandertals (Arcy-sur-Cure, France).
J Hum Evol
December 2024
Univ. Paris 1 Panthéon-Sorbonne, Univ. Paris Ouest Nanterre La Défense, MSH Mondes-CNRS-Ministère de la Culture, ArScAn, UMR 7041, 92000, Nanterre, France.
The Grotte du Bison, in Arcy-sur-Cure (Yonne, France), yielded a large assemblage of 49 Neandertal remains from late Mousterian layers, offering critical insights for the study of Middle to Upper Paleolithic populations of Western Europe. Previous studies described the external morphology of 13 isolated teeth and a partial maxilla. Building on this previous work, the current study provides further descriptions and analyses of the remains, including one postcranial fragment, six cranial fragments, two maxillary fragments, and 40 isolated teeth.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!