Low Complexity Regions (LCRs) are segments of proteins with a low diversity of amino acid composition. These regions play important roles in proteins. However, annotations describing these functions are dispersed across databases and scientific literature. LCRAnnotationsDB aims to consolidate knowledge about LCRs and store relevant annotations in a single place. To unify redundant annotations, we assigned them categories based on similarity in function, protein structure, and biological process. Categories are organized hierarchically by linking them to Gene Ontology terms. The LCRAnnotationsDB database can be accessed at https://lcrannotdb.lcr-lab.org/ .

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12864-024-10960-5DOI Listing

Publication Analysis

Top Keywords

lcrannotationsdb database
8
low complexity
8
complexity regions
8
database low
4
regions functional
4
functional structural
4
annotations
4
structural annotations
4
annotations low
4
regions lcrs
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!