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http://dx.doi.org/10.1245/s10434-024-16803-7 | DOI Listing |
Ann Surg Oncol
December 2024
Department of Cardiothoracic Surgery, Weill Cornell Medicine, New York-Presbyterian Hospital, New York, NY, USA.
Philos Trans A Math Phys Eng Sci
December 2024
Department of Physics, University of Strathclyde, John Anderson Building, 107 Rottenrow, Glasgow G4 0NG, UK.
We present a brief introduction to the quantum theory of light as it is understood in the field of quantum optics. Our aim is not to review the topic, which would require a very extensive article (or even a book of several volumes) but rather to provide sufficient background to set the ideas in the following papers in their correct context.This article is part of the theme issue 'The quantum theory of light'.
View Article and Find Full Text PDFInt J Comput Assist Radiol Surg
December 2024
IFCARS, Küssaberg, Germany.
Purpose: Based on CARS Congress events selected from its 40 year history, this editorial summarises the main challenges and solution concepts encountered, and what the future may hold for a model-centric world view in the specific domain of computer assisted radiology and surgery.
Methods: Altogether some 15,000 publications appeared in the CAR/CARS Congress Proceedings and Journal between 1985 and 2025, comprising approximately 3000 full papers and 12,000 long abstracts. Modelling occupied a central theme in many of these publications, particularly in the 2020s.
Int J Surg
October 2024
Emeritus Professor of Surgery, Campus Biomedico University, Fondazione Policlinico Campus Biomedico, Rome, Italy.
Despite an increased understanding of the underlying biology of the disease, pancreatic ductal adenocarcinoma (PDAC) remains a challenging condition with poor outcomes and a 5-year survival rate, even at an early stage, of less than 10%. This dismal prognosis is due in part to biological aggressiveness, the lack of early diagnosis, suboptimal surgical selection, and the need for effective neoadjuvant and adjuvant therapies. However, progress is being made with significant advancements in the diagnosis, staging, and treatment of PDAC, with a focus on precision therapy, improved surgical care, and supportive care, coupled with a deeper understanding of PDAC's biology.
View Article and Find Full Text PDFFront Immunol
December 2024
Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Würzburg, Germany.
Background: Merkel cell carcinoma (MCC) is a rare but highly aggressive cutaneous malignancy. Immune checkpoint inhibition (ICI) with PD-(L)1 blockade has significantly improved treatment outcomes in metastatic disease. In patients with primary resistance to PD-(L)1 inhibition, a high overall response rate (ORR) of 50% to later-line ipilimumab plus nivolumab (IPI/NIVO) has been demonstrated.
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