Chronic wounds are a syndrome that affects around 4% of the world population due to several pathologies. The COV-19 pandemic has enforced the need of developing new techniques and technologies that can help clinicians to monitor the affected patients easily and reliably. In this prospective observational study a new device, the Wound Viewer, that works through a memristor-based Discrete-Time Cellular Neural Network (DT-CNN) has been developed and tested through a clinical trial of 150 patients. The WV has been developed to serve as the state-of-art tool, capable to return the actual clinical information that is most needed by the caregivers: through the WBP scale, it classifies four classes of wounds by the type of tissue: A-only granular tissue; B-<50% slough; C->50% slough; D-necrosis. This work aims to describe in depth the technology and the computational techniques that have been implemented, and to demonstrate reliability in automatically identifying, classifying through internationally accepted clinical scales and measuring such wounds, that peaked to over a 90% of accuracy.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1038/s41598-024-81521-9 | DOI Listing |
BMC Pulm Med
December 2024
School of Nursing, Jinan University, Guangzhou, China.
Objectives: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide, particularly among the elderly, resulting in high rates of intensive care unit (ICU) admissions. Malnutrition is common in elderly patients and has been associated with poor prognosis in patients with COPD. However, its impact in the ICU setting remains incompletely defined.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Raebareli (NIPER-R), Transit Campus, Bijnor-Sisendi Road, Sarojini Nagar, Near CRPF Base Camp, Lucknow, UP 226002, India. Electronic address:
Exosomal non-coding RNAs (ncRNAs), including miRNAs, lncRNAs, and circRNAs, have emerged as crucial modulators in cellular signaling, influencing wound healing processes. Stem cell-derived exosomes, which serve as vehicles for these ncRNAs, show remarkable therapeutic potential due to their ability to modulate wound healing stages, from initial inflammation to collagen formation. These ncRNAs act as molecular signals, regulating gene expression and protein synthesis necessary for cellular responses in healing.
View Article and Find Full Text PDFJ Plast Reconstr Aesthet Surg
November 2024
Bagcilar Training and Research Hospital, Department of Plastic, Reconstructive and Aesthetic Surgery, Istanbul, Turkey.
Objective: Autoimmune diseases are systemic conditions that can have negative effects on wound healing. The objective of the present study was to investigate the efficacy of combining bone marrow-derived mesenchymal stem cells (BM-MSCs), acellular dermal matrix (ADM), split-thickness skin graft (STSG), and negative-pressure wound therapy (NPWT) for treating patients with autoimmune diseases and chronic non-healing wounds.
Methods: Thirty-four patients with autoimmune diseases and non-healing chronic wounds of the lower extremities between 2012 and 2023 were included in the study.
Vestn Oftalmol
December 2024
AO Meditsina (Academician Roytberg's Clinic), Moscow, Russia.
Purpose: This study was conducted to identify the group at highest risk for autoimmune inflammation through a comparative analysis among patients with chronic post-traumatic uveitis (CPTU).
Material And Methods: The clinical group included 50 patients (aged 18 to 87 years, mean age 41±2.6 years) with CPTU resulting from penetrating injury, contusion, or intraocular surgery.
Langenbecks Arch Surg
December 2024
Shaheed Mohtarma Benazir Bhutto Medical College Lyari, Lyari Hospital Rd, Rangiwara Karachi, Karachi City, Sindh, 75010, Pakistan.
To the Editor,I would like to acknowledge the valuable efforts taken to enhance the knowledge through the article "Prediction model for poor short-term prognosis in patients with chronic subdural hematoma (CSDH) after burr hole drainage: a retrospective cohort study" [1]. We thoroughly read this article published in your journal and learned the aim behind this study. This article has described every aspect of determining prognosis postoperatively in patients after evacuation of chronic subdural hematoma via a single burr hole.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!