This study investigates the production of graphene-enhanced polyethylene terephthalate glycol (G-PETG) components using fused deposition modeling (FDM) and evaluates their mechanical properties, contributing to the advancement of additive manufacturing. Trials demonstrated notable improvements in mechanical performance, with optimal printing parameters identified using the Spice Logic Analytical Hierarchy Process (AHP). The effectiveness of this methodology is further compared with the Fuzzy Analytic Hierarchy Process (FAHP) combined with the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS). The study revealed significant enhancements, with the ultimate tensile strength (UTS) reaching 69.1 MPa, an average Young's modulus of 735.6 MPa, and an ultimate compressive strength (UCS) of 85.3 MPa. These findings provide valuable insights into optimizing techniques for improving the mechanical performance of G-PETG components, advancing material applications in various industries.
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http://dx.doi.org/10.1038/s41598-024-80376-4 | DOI Listing |
Int J Pharm
December 2024
Beijing Institute of Radiation Medicine, Beijing 100850, China. Electronic address:
Cannabidiol (CBD) is widely used to alleviate the syndromes of epilepsy. However, the marketed oral CBD formulation has the prominent first-pass effect. Here, a cannabidiol-loaded hollow suppository (CHS) was developed using three-dimensional (3D) printing technology.
View Article and Find Full Text PDFSci Rep
December 2024
Centre for Sustainable Materials and Surface Metamorphosis, Chennai Institute of Technology, Chennai, 600069, Tamilnadu, India.
This study investigates the production of graphene-enhanced polyethylene terephthalate glycol (G-PETG) components using fused deposition modeling (FDM) and evaluates their mechanical properties, contributing to the advancement of additive manufacturing. Trials demonstrated notable improvements in mechanical performance, with optimal printing parameters identified using the Spice Logic Analytical Hierarchy Process (AHP). The effectiveness of this methodology is further compared with the Fuzzy Analytic Hierarchy Process (FAHP) combined with the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS).
View Article and Find Full Text PDFDrug Dev Ind Pharm
December 2024
Gazi University, Faculty of Pharmacy, Department of Pharmaceutical Technology, 06330 Etiler, Ankara, Türkiye.
Introduction: This study aims to develop immediate release tablet formulations of lornoxicam (LRX) using hot melt extrusion (HME)-based fused deposition modelling (FDM) focusing on the adjustment of drug release by arranging infill densities and evaluating microcrystalline cellulose II (MCC II) as a disintegrating agent for HME-FDM purposes. LRX is a poorly soluble drug that exhibits pH-dependent solubility with a high thermal degradation temperature. These characteristics make it an ideal model drug for the HME-based FDM technique.
View Article and Find Full Text PDFOrthop Surg
December 2024
Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China.
Background: High tibial osteotomy (HTO) is a surgical procedure for treating certain knee conditions. Proper execution of HTO can preserve joint function and delay or avoid the need for total knee replacement. This study compared different 3D printing techniques (fused deposition modeling, selective laser sintering, and direct metal laser sintering) and a navigation system for their suitability in assisting HTO surgeries.
View Article and Find Full Text PDFCurr Pharm Des
December 2024
Institute of Pharmaceutical Research, GLA University, Mathura-Delhi Road, Mathura-281406, Uttar Pradesh, India.
Research on shape memory materials (SMM) or smart materials, along with advancements in printing technology, has transformed three-dimensional (3D) printing into what we now refer to as 4D printing. In this context, the addition of time as a fourth dimension enhances 3D printing. 4D printing involves the creation of 3D-printed objects that can change their shapes into complex geometries when influenced by external stimuli such as temperature, light, or pH over time.
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