The potential role of vesicle transport-related small GTPases rabs in abiotic stress responses.

Rab GTPases are a class of small GTP-binding proteins, play crucial roles in the membrane transport machinery with in eukaryotic cells. They dynamically regulate the precise targeting and tethering of transport vesicles to specific compartments by transitioning between active and inactive states. In plants, Rab GTPases are classified into eight distinct subfamilies: Rab1/D, Rab2/B, Rab5/F, Rab6/H, Rab7/G, Rab8/E, Rab11/A, and Rab18/C. Their functional specificity is often attributed to their cellular localization. This paper reviews provides a comprehensive review of the pivotal roles played by Rab GTPases in plant intracellular transport and their significant contributions to abiotic stress responses. Additionally, it critically examines the identified activators and effectors associated with these proteins. In the context of abiotic stress, Rab GTPases play a crucial role in regulating vesicle transport and secretion, thereby enhancing plant adaptability and survival under adverse conditions such as drought, salt stress, and low temperatures. By mediating these intricate processes, Rab GTPases actively contribute to maintaining cellular homeostasis and improving stress resilience - factors that are indispensable for sustainable agricultural development and ecosystem stability.