The Chinese guidelines for ultrasound-guided thermal ablation of thyroid nodules (2024 edition) were jointly initiated by the Ultrasound Committee of Chinese Medical Association, the Interventional Ultrasound Committee of Chinese Association of Ultrasound in Medicine and Engineering, the Ultrasonic Intervention Committee of Chinese Colleges of Interventionalists, and the Oncological Intervention Committee of Chinese Research Hospital Association; 37 multidisciplinary experts in interventional ultrasound, ultrasound medicine, endocrinology, and thyroid surgery participated in the compilation of this guide, which expanded the depth and breadth of the perspective and enhanced the authority of the guide. Based on the systematic review of literature related to ultrasound-guided thermal ablation of thyroid nodules and the professional opinions of experts, the guidelines define the indications and contraindications of thermal ablation, including pre-ablation evaluation and preparation, thermal ablation techniques and operational procedures, post-ablation follow-up, therapeutic effect evaluation, complication prevention and treatment, and the writing of medical documents for ablation. According to the Grading of Recommendations Assessment, Development, and Evaluation (GRADE), a total of 17 objective and comprehensive recommendations were given. The publication and promotion of this guideline will play a positive role in promoting the standardization of ultrasound-guided thermal ablation of thyroid nodules.
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http://dx.doi.org/10.1097/JS9.0000000000002209 | DOI Listing |
J Urol
March 2025
Division of Urologic Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Purpose: Cryoablation (CA) and partial nephrectomy (PN) are effective nephron-sparing treatments for small renal masses. While guidelines list thermal ablation as an option for tumors <3 cm, limited data compare PN and CA in larger tumors. We compared intermediate-term oncologic outcomes between PN and CA in renal masses >3 cm.
View Article and Find Full Text PDFJ Gastrointest Cancer
March 2025
Department of Interventional Therapy, National Cancer Centre/National Clinical Research Centre for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Objective: To compare early recurrence patterns, safety, survival and investigate the clinical risk factors of early recurrence (ER) after liver resection or thermal ablation (TA) for patients with colorectal liver metastases (CRLM) with number ≤ 5 and largest diameter ≤ 3 cm.
Materials And Methods: This retrospective study included patients with CRLM who underwent liver resection or TA between January 2016 and December 2021 at two hospitals in China. The Kaplan-Meier method and log-rank test were used to assess recurrence-free survival (RFS) and overall survival (OS).
Small
March 2025
State Key Laboratory of Advanced Medical Materials and Devices, Medical College, Tianjin University, Tianjin, 300072, China.
Irreversible electroporation (IRE) is a minimally invasive, non-thermal tumor ablation technique that induces nanoscale membrane perforation, leading to immunogenic cell death (ICD). However, IRE alone is limited by uneven electric field attenuation, incomplete tumor ablation, and the immunosuppressive nature of the tumor microenvironment. To address these challenges, a multifunctional nanomaterial, vermiculite nanosheets/calcium peroxide nanosheets (VMT/CaO NSs), is developed to enhance the efficacy of IRE.
View Article and Find Full Text PDFNatl Sci Rev
April 2025
Center for X-Mechanics, Department of Engineering Mechanics, Zhejiang University, Hangzhou 310027, China.
Gallium-based liquid metals, when combined with magnetic agents, emerge as intelligent materials with potential applications in soft robotics within biomedical engineering. However, concerns have arisen from the residual presence of liquid metal, raising long-term biological risks. Herein, we propose a containment method that involves the rolling of magnetic liquid-metal droplets in lyophilized powders, resulting in the formation of intact hydrogel coatings upon hydration.
View Article and Find Full Text PDFJ Neurosurg Case Lessons
March 2025
Department of Neurology, Washington University School of Medicine, St. Louis, Missouri.
Background: Despite rapid adoption among many epilepsy centers across the United States, stereotactic magnetic resonance imaging (MRI) thermometry-guided laser interstitial thermal therapy (LITT) is not universally available to treat medically refractory epilepsy in appropriately selected patients.
Observations: The authors present two cases in which patients with mesial temporal lobe epilepsy (MTLE)-one with stereoelectroencephalography-proven left MTLE and one with right mesial temporal sclerosis-were advised to undergo LITT by a multidisciplinary team, but an insurance provider refused preauthorization, prompting the use of radiofrequency ablation (RFA) instead. In each case, the authors utilized a disposable direct MRI guidance stereotactic frame and a commercially available RFA probe with direct thermistor measurements under general anesthesia.
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