Organometallic Photocatalyst-Promoted Synthesis and Modification of Carbohydrates under Photoirradiation.

Carbohydrates are natural, renewable, chemical compounds that play crucial roles in biological systems. Thus, efficient and stereoselective glycosylation is an urgent task for the preparation of pure and structurally well-defined carbohydrates. Photoredox catalysis has emerged as a powerful tool in carbohydrate chemistry, providing an alternative for addressing some of the challenges of glycochemistry. Over the last few decades, Ir- and Ru-based organometallic photocatalysts have attracted significant interest because of their high stability, high-energy triplet state, strong visible-light absorption, long luminescence lifetime, and amenability to ligand modification. This review highlights the recent progress in the organometallic photocatalyst-promoted synthesis and modification of carbohydrates under photoirradiation, as well as the related benefits and drawbacks.