The Bologna Process and the European Higher Education Area (EHEA) are celebrating 25 years of free mobility and career opportunities. Despite its progress, disparities exist in the effectiveness of this initiative across EHEA countries. Physiology is a mandatory component of health science curricula but lacks standardized educational benchmarks, leading to limited societal awareness and professional opportunities. In contrast, there is a different dynamic in the USA, where physiology is a profession with growing opportunities. Within Europe, national scientific societies are actively promoting physiology education and research but societal awareness and physiology related knowledge and opportunities are still limited. A recent study on the Portuguese reality revealed that while physiology is taught at many institutions, there is significant variability in hands-on training between universities and technical colleges. Notably, only a small percentage of faculty have published in physiology journals, suggesting a diluted identity for the discipline. Challenges in harmonization and training reflect a need for stronger collaboration among scientific organizations to improve physiology teaching and research across Europe. By addressing these issues, the future of physiology can be strengthened, ensuring better recognition and professional development for physiologists in the EHEA.
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http://dx.doi.org/10.14814/phy2.70148 | DOI Listing |
J Clin Invest
January 2025
Department of Biochemistry, Molecular Biology & Biophysics, University of Minnesota, Minneapolis, United States of America.
Eccentric contraction- (ECC) induced force loss is a hallmark of murine dystrophin-deficient (mdx) skeletal muscle that is used to assess efficacy of potential therapies for Duchenne muscular dystrophy. While virtually all key proteins involved in muscle contraction have been implicated in ECC force loss, a unifying mechanism that orchestrates force loss across such diverse molecular targets has not been identified. We showed that correcting defective hydrogen sulfide (H2S) signaling in mdx muscle prevented ECC force loss.
View Article and Find Full Text PDFGM Crops Food
December 2025
School of Life Science, Henan University, Kaifeng, Henan, People's Republic of China.
Malic acid markedly affects watermelon flavor. Reducing the malic acid content can significantly increase the sweetness of watermelon. An effective solution strategy is to reduce watermelon malic acid content through molecular breeding technology.
View Article and Find Full Text PDFPharmacol Rep
January 2025
Laboratory of Translational Physiology and Pharmacology, Pharmaceutical Sciences Graduate Program, Vila Velha University (UVV), R Mercurio s/n, Vila Velha, ES, 29102623, Brazil.
Background: The therapeutic targeting of the intestinal microbiota has gained increasing attention as a promising avenue for addressing mood disorders. This study aimed to assess the potential effect of supplementing standard pharmacological treatment with the probiotic kefir in patients with Major Depressive Disorder (MDD).
Methods: Thirty-eight female participants diagnosed with moderate MDD by the Hamilton Rating Scale for Depression (HAM-D) were selected to receive the probiotic kefir in conjunction with antidepressant therapy for 12 weeks.
Curr Osteoporos Rep
January 2025
Department of Immunology, Tufts University, Boston, MA, 02111, USA.
Purpose Of Review: The purpose of this review is to summarize the current understanding of cell-autonomous innate immune pathways that contribute to bone homeostasis and disease.
Recent Findings: Germ-line encoded pattern recognition receptors (PRRs) are the first line of defense against danger and infections. In the bone microenvironment, PRRs and downstream signaling pathways, that mount immune defense, interface intimately with the core cellular processes in bone cells to alter bone formation and resorption.
Eur J Sport Sci
February 2025
School of Human Sciences (Exercise and Sport Science), The University of Western Australia, Perth, Australia.
End-range movements are among the most demanding but least understood in the sport of tennis. Using male Hawk-Eye data from match-play during the 2021-2023 Australian Open tournaments, we evaluated the speed, deceleration, acceleration, and shot quality characteristics of these types of movement in men's Grand Slam tennis. Lateral end-range movements that incorporated a change of direction (CoD) were identified for analysis using k-means (end-range) and random forest (CoD) machine learning models.
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