This study explores the performance of the item response tree (IRTree) approach in modeling missing data, comparing its performance to the expectation-maximization (EM) algorithm and multiple imputation (MI) methods. Both simulation and empirical data were used to evaluate these methods across different missing data mechanisms, test lengths, sample sizes, and missing data proportions. Expected a posteriori was used for ability estimation, and bias and root mean square error (RMSE) were calculated. The findings indicate that IRTree provides more accurate ability estimates with lower RMSE than both EM and MI methods. Its overall performance was particularly strong under missing completely at random and missing not at random, especially with longer tests and lower proportions of missing data. However, IRTree was most effective with moderate levels of omitted responses and medium-ability test takers, though its accuracy decreased in cases of extreme omissions and abilities. The study highlights that IRTree is particularly well suited for low-stakes tests and has strong potential for providing deeper insights into the underlying missing data mechanisms within a data set.
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http://dx.doi.org/10.1177/00131644241306024 | DOI Listing |
Cochrane Database Syst Rev
January 2025
Department of Rehabilitation Medicine, Amsterdam UMC, location University of Amsterdam, Meibergdreef 9, Amsterdam, Netherlands.
Background: Calf muscle weakness is a common symptom in slowly progressive neuromuscular disorders that lead to walking problems like instability and increased walking effort. The mainstay of treatment to improve walking in this population is the provision of ankle-foot-orthoses (AFOs). Since we are not aware of an up-to-date and complete overview of the effects of AFOs used for calf muscle weakness in slowly progressive neuromuscular disorders, we reviewed the evidence for the effectiveness of AFOs to improve walking in this patient group, in order to support clinical decision-making.
View Article and Find Full Text PDFJ Cachexia Sarcopenia Muscle
February 2025
Center for Health Information Partnerships, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Background: Cancer-associated cachexia can inhibit immune checkpoint inhibitor (ICI) therapy efficacy. Cachexia's effect on ICI therapy has not been studied in large cohorts of cancer patients aside from lung cancer. We studied associations between real-world routinely collected clinical cachexia markers and disability-free, hospitalization-free and overall survival of cancer patients.
View Article and Find Full Text PDFAdv Appl Bioinform Chem
January 2025
Department of Information Technology, Mutah University, Al-Karak, Jordan.
Purpose: The incidence of cancer, which is a serious public health concern, is increasing. A predictive analysis driven by machine learning was integrated with haematology parameters to create a method for the simultaneous diagnosis of several malignancies at different stages.
Patients And Methods: We analysed a newly collected dataset from various hospitals in Jordan comprising 19,537 laboratory reports (6,280 cancer and 13,257 noncancer cases).
Open Forum Infect Dis
January 2025
Harvard Medical School, Boston, Massachusetts, USA.
Background: Infections by and influenza viruses are vaccine-preventable diseases causing great morbidity and mortality. We evaluated pneumococcal and influenza vaccination practices during pre-international travel health consultations.
Methods: We evaluated data on pretravel visits over a 10-year period (1 July 2012 through 31 June 2022) from 31 sites in Global TravEpiNet (GTEN), a consortium of US healthcare facilities providing pretravel health consultations.
Front Antibiot
March 2024
Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Antimicrobial resistance in bacteria has been associated with significant morbidity and mortality in hospitalized patients. In the era of big data and of the consequent frequent need for large study populations, manual collection of data for research studies on antimicrobial resistance and antibiotic use has become extremely time-consuming and sometimes impossible to be accomplished by overwhelmed healthcare personnel. In this review, we discuss relevant concepts pertaining to the automated extraction of antibiotic resistance and antibiotic prescription data from laboratory information systems and electronic health records to be used in clinical studies, starting from the currently available literature on the topic.
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