Exploring Ocular Disorders in Parkinson's Disease: A Comprehensive Review and Future Perspectives.

Exp Eye Res

Centre for Eye and Vision Research (CEVR), 17W Hong Kong Science Park, Hong Kong; Research Centre for Chinese Medicine Innovation, The Hong Kong Polytechnic University, Kowloon, Hong Kong; Department of Food Science and Nutrition, The Hong Kong Polytechnic University, Kowloon, Hong Kong. Electronic address:

Published: December 2024

AI Article Synopsis

  • Parkinson's disease (PD) is primarily known for its motor symptoms, but research is highlighting its significant effects on non-motor functions, particularly ocular health.
  • This review discusses the connection between PD and various common eye diseases, including dry eye disease and cataracts, emphasizing that these ocular issues can serve as early indicators of PD.
  • Future studies should focus on exploring links between PD and additional eye conditions, like myopia, to develop better treatment approaches for patients.

Article Abstract

Parkinson's disease (PD) is a multifaceted neurodegenerative disorder characterized by predominantly motor symptoms. However, recent research has broadened our understanding of PD by revealing its impact on non-motor functions, including ocular manifestations. This review explored the intricate relationship between PD and ocular health, shedding light on the mechanisms underlying common ocular diseases such as dry eye disease, cataract, glaucoma, age-related macular degeneration, and diabetic retinopathy. It also underscores the importance of recognizing ocular manifestations as potential early markers of PD, as well as their impact on patients' daily activities, necessitating prompt identification and intervention to prevent complications and enhance the overall quality of life. Furthermore, future research should prioritize unraveling the potential association between PD and other prevalent ocular diseases, such as myopia, to formulate effective treatment strategies.

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Source
http://dx.doi.org/10.1016/j.exer.2024.110225DOI Listing

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