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Antipsychotic-Induced Tardive Lingual Dystonia Presenting With Bradycardia.
Prim Care Companion CNS Disord
December 2024
Department of Psychiatry, All Indian Institute of Medical Sciences Bibinagar, Hyderabad, Telangana, India.
Antipsychotics and chronic dystonia at a Botulinum Toxin clinic.
S Afr J Psychiatr
September 2024
Department of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
Article Synopsis
- The study focuses on adults with chronic dystonia, especially those whose condition is linked to antipsychotic medication use, highlighting the clinical challenges involved.
- It analyzes 119 patients from a Botulinum Toxin Clinic in Cape Town, revealing that individuals with antipsychotic-induced dystonia are generally younger, more likely to be female, and require more intensive Botulinum toxin treatment.
- The findings indicate a notable link between the type of dystonia and additional mental health issues, suggesting the need for improved patient management strategies in this population.
Effectiveness of Vitamin E in Treatment of Antipsychotic-Induced Tardive Dyskinesia and Extrapyramidal Symptoms: A Case Report.
Cureus
August 2024
Psychiatry, Al Amal Psychiatric Hospital, Emirates Health Services, Dubai, ARE.
Antipsychotic medications, while crucial in managing severe psychiatric disorders such as schizophrenia and bipolar disorder, are frequently associated with extrapyramidal symptoms (EPS) and tardive dyskinesia (TD). TD, characterized by repetitive, involuntary movements, especially of the face and limbs, poses a substantial clinical challenge due to its often irreversible nature. Conventional management strategies, including dose reduction and switching to atypical antipsychotics, frequently offer limited success, prompting exploration of alternative therapies.
View Article and Find Full Text PDFAtypical Antipsychotic-Induced Tardive Dyskinesia in a Middle-Aged Schizophrenic Patient: A Case Report.
Cureus
July 2024
Department of Psychiatry, Bahrain Psychiatric Hospital, Manama, BHR.
Tardive dyskinesia (TD) is a potentially irreversible movement disorder characterized by involuntary, repetitive movements, most commonly affecting the face, tongue, and extremities. It is primarily associated with the long-term use of first-generation (typical) antipsychotics but can also occur with second-generation (atypical) antipsychotics such as aripiprazole. Despite its lower risk profile, aripiprazole can induce TD, as illustrated by a 45-year-old woman with schizophrenia who developed severe involuntary movements after five years of stable treatment with this medication.
View Article and Find Full Text PDFChronic Cocaine Use and Parkinson's Disease: An Interpretative Model.
Int J Environ Res Public Health
August 2024
VP Dole Research Group, G. De Lisio Institute of Behavioural Sciences, Via di Pratale 3, 56121 Pisa, Italy.
Article Synopsis
- Cocaine use has become a significant public health issue, with roughly 24.6 million users globally and 1 million diagnosed with cocaine use disorder, according to the 2023 World Drug Report.
- While short-term effects of cocaine are well-documented, there is a lack of comprehensive data on its medium and long-term impacts, which suggest increased risks for cardiovascular issues and neurodegenerative diseases.
- The paper proposes that chronic cocaine use leads to neurobiological changes affecting neurotransmitter systems, particularly dopaminergic pathways, which may increase vulnerability to neurodegenerative disorders and highlights the need for further research to inform therapeutic interventions.
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