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http://dx.doi.org/10.1097/01.NAJ.0001096892.96809.d2 | DOI Listing |
Biomacromolecules
December 2024
MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310058, China.
-Acetyl cysteine (NAC) is an essential molecule that boosts acute lung injury (ALI) defense via its direct antioxidant capability. Nevertheless, the therapeutic use of NAC is limited due to its poor bioavailability and short half-life. In this study, NAC was grafted to the polyurethane consisting of poly(propylene fumarate), poly(thioketal), and 1,6-hexamethylene diisocyanate (PFTU) to reduce excessive oxidative stress and inflammatory factors in ALI.
View Article and Find Full Text PDFInt J Pharm
December 2024
Department of Food Science and Biotechnology, College of Life Sciences, Sejong University, Seoul, South Korea. Electronic address:
The biosynthesis of nanomaterials is a vast and expanding field of study due to their applications in a variety of fields, particularly the pharmaceutical and biomedical fields. Various synthetic routes, including physical and chemical methods, have been developed in order to generate metal nanoparticles (NPs) with definite shapes and sizes. In this review, focused on the recent advancements in the green synthetic methods for the generation of silver, zinc and copper NPs with simple and eco-friendly approaches and the potential of the biosynthesized metal and metal oxide NPs as alternative and therapeutic agent for the treatment of inflammatory diseases.
View Article and Find Full Text PDFFront Vet Sci
December 2024
Department of Radiobiology, Military Faculty of Medicine, University of Defence, Hradec Kralove, Czechia.
The past 30 years have brought undeniable progress in medicine, biology, physics, and research. Knowledge of the nature of the human body, diseases, and disorders has been constantly improving, and the same is true regarding their treatment and diagnosis. One of the greatest advances in recent years has been the introduction of nanoparticles (NPs) into medicine.
View Article and Find Full Text PDFErgonomics
December 2024
Orano, NPS, Saint Quentin en Yvelines, France.
This paper presents a constructive view of Human Factors/Ergonomics (HFE) and its implications regarding work, organisations and HFE interventions. In contrast to a defensive approach to HFE, which would view work mostly as a source of constraints, and the role of HFE as reducing these constraints, the goal of constructive ergonomics is to eliminate obstacles hindering success and development and to maximise opportunities for acting and learning. After having developed the concept and the methods of enabling interventions, as well as their consequences on the role of ergonomists, two enabling interventions are presented to illustrate the implementation of the constructive approach in real work settings.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!