Pomegranate, hawthorn, gilaburu, blackberry, and rosehip vinegar postbiotic solutions (VPS) were produced by traditional methods. The bioactive components of VPS, antioxidant capacity, antimicrobial activities, minimum inhibition concentration (MIC), and minimum bactericidal concentration (MBC) assays were determined. While rosehip VPS has the highest amount of lactic acid, phenolic and flavonoids, gilaburu VPS has the highest butyric acid. The highest antimicrobial activities were observed for hawthorn VPS on and , for gilaburu VPS on and , for blackberry VPS on mold and , for pomegranate VPS on and and for rosehip VPS on and . Moreover, the mortality values were reported as MBCs: hawthorn for (94.6% at 0.03 mg mL) and A (94.1% at 0.03 mg mL), gilaburu for (93.4% at 0.06 mg mL) and (93.2% at 0.13 mg mL), rosehip for and (93.7-91.7% at 0.06 mg mL), pomegranate for methicillin-resistant (96.0% at 0.5 mg mL), and blackberry for (91.3% at 0.25 mg mL) and (92.1% at 0.13 mg mL), in addition to an equal mixture of the five VPSs for and (85.6% at 0.06 mg mL). The MICs for VPS were generally found in a 0.5 mg mLdilution of each vinegar. Remarkably, common and local fruits can be rich sources of bioactive components without the need for imported products or expensive processing methods or equipment. This study demonstrated that rosehip VPS has the greatest potential as both a nutrient and a natural disinfectant.
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http://dx.doi.org/10.1002/fsn3.4459 | DOI Listing |
Food Sci Nutr
December 2024
Department of Veterinary Science, Technical Sciences Vocational School Batman University Batman Turkey.
Pomegranate, hawthorn, gilaburu, blackberry, and rosehip vinegar postbiotic solutions (VPS) were produced by traditional methods. The bioactive components of VPS, antioxidant capacity, antimicrobial activities, minimum inhibition concentration (MIC), and minimum bactericidal concentration (MBC) assays were determined. While rosehip VPS has the highest amount of lactic acid, phenolic and flavonoids, gilaburu VPS has the highest butyric acid.
View Article and Find Full Text PDFJ Clin Neurosci
February 2024
Department of Neurological Surgery, Cleveland Clinic, Cleveland, OH, United States; Cerebrovascular Center, Cleveland Clinic, Cleveland, OH, United States. Electronic address:
Background: Aneurysmal subarachnoid hemorrhage (aSAH) can be devastating. Identifying predisposing factors is paramount in reducing aSAH-related mortality. Obesity's negative impact on health is well-established.
View Article and Find Full Text PDFCPT Pharmacometrics Syst Pharmacol
August 2023
Rosa & Co, San Carlos, California, USA.
Virtual patients (VPs) are widely used within quantitative systems pharmacology (QSP) modeling to explore the impact of variability and uncertainty on clinical responses. In one method of generating VPs, parameters are sampled randomly from a distribution, and possible VPs are accepted or rejected based on constraints on model output behavior. This approach works but can be inefficient (i.
View Article and Find Full Text PDFNeurol India
June 2021
Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India.
Background: Ventriculoperitoneal shunt (VPS) is the most common procedure used in the management of hydrocephalus regardless of the etiology. The standard free-hand technique is used for the placement of VPS in patients with enlarged ventricles. In patients with very small ventricles, CSF access through ventriculostomy becomes challenging and free-hand technique may be associated with high failure rates.
View Article and Find Full Text PDFPharm Biol
July 2010
M.V.P.S. College of Pharmacy, Gangapur Road, Shivaji Nagar, Nashik-422 002, Maharashtra, India.
Context: The ischemic brain lesions induced in rats by temporary occlusion of the bilateral common carotid arteries and restoration of blood flow to an ischemic brain region is associated with generation of reactive oxygen species with consequent reperfusion injury.
Objective: The present study investigated the neuroprotective potential of Hibiscus rosa sinensis L. (Malvaceae) in a bilateral common carotid artery (BCCA) occlusion model of global cerebral ischemic reperfusion.
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