Introduction: Inhalation injury may be associated with increased risk of dysphonia and laryngotracheal pathology; however, presentation and recovery patterns are not well documented.
Objectives: To examine the prevalence, clinical characteristics, and recovery patterns of dysphonia and laryngeal pathology following inhalation injury.
Methods: A retrospective audit was conducted of all burn patients with diagnosed inhalation injury admitted to two Australian burn units over ten years. Demographic, burn, and critical care data were collected in addition to voice and laryngeal outcomes.
Results: Inhalation injury was confirmed in 167 patients (75 % male, mean age 45 years, mean TBSA 23 %, 90 % head/neck burns, 11 % tracheostomy, mean intubation 7 days, mean ICU length of stay [LOS] 11 days, total LOS 39 days). Laryngeal pathology included oedema/erythema, laryngeal granulation, vocal cord palsy/paresis, and laryngeal contracture. Dysphonia was observed in 55%, increasing to 87 % in those with severe inhalation injury (n = 62). By 6 months, dysphonia had resolved in 98 % of the non-severe and 73 % of the severe cohort. Severe inhalation injury was associated with dysphonia (p < 0.001), poor dysphonia resolution at six months (p < 0.001), and duration of intubation (p = 0.033).
Conclusion(s): Dysphonia occurs in one of every two burn patients with inhalation injury, and a quarter of patients with severe injury will still have persistent dysphonia at six months.
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http://dx.doi.org/10.1016/j.burns.2024.107321 | DOI Listing |
Ann Ital Chir
December 2024
Department of Anesthesiology, Institute of Anesthesia, Emergency and Critical Care, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, 225002 Yangzhou, Jiangsu, China.
Aim: Intraoperative lung-protective ventilation strategies (LPVS) have been shown to improve lung oxygenation and prevent postoperative pulmonary problems in surgical patients. However, the application of positive end-expiratory pressure (PEEP)-based LPVS in emergency traumatic brain injury (TBI) has not been thoroughly explored. The purpose of this study is to evaluate the effects of drive pressure-guided individualized PEEP on perioperative pulmonary oxygenation, postoperative pulmonary complications, and recovery from neurological injury in patients with TBI.
View Article and Find Full Text PDFBurns
December 2024
Parkland Health, 5200 Harry Hines Blvd, Dallas, TX 75235, USA. Electronic address:
Health and racial disparities can limit access to preventative, trauma, and chronic disease care but have not been addressed in burn resuscitation. Over- and under-resuscitation contribute to increased overall hospital costs, and morbidity and mortality rates. The primary objective of this study was to identify potential racial disparities that may exist during the initial fluid resuscitation after burn injury.
View Article and Find Full Text PDFBurns
November 2024
Burns Unit, Concord Repatriation General Hospital, Sydney, NSW, Australia; Faculty of Medicine & Health, The University of Sydney, Sydney, NSW, Australia.
Introduction: Inhalation injury may be associated with increased risk of dysphonia and laryngotracheal pathology; however, presentation and recovery patterns are not well documented.
Objectives: To examine the prevalence, clinical characteristics, and recovery patterns of dysphonia and laryngeal pathology following inhalation injury.
Methods: A retrospective audit was conducted of all burn patients with diagnosed inhalation injury admitted to two Australian burn units over ten years.
Ann Work Expo Health
December 2024
HSE Science Division, Health and Safety Executive's Science and Research Centre, Harpur Hill, Buxton SK17 9JN, United Kingdom.
Desktop three-dimensional (3D) printers are used in businesses, schools, and colleges, and are generally of an unenclosed design which may give rise to injuries or inhalation exposure to emissions of small particles (<1 µm) and volatile organic compounds (VOCs). The aim of this work was to explore the health risks related to the use of desktop 3D printers in workplaces in the United Kingdom. A digital survey on the use of desktop 3D printers was completed voluntarily and anonymously between February and June 2023, receiving 146 responses.
View Article and Find Full Text PDFFood Chem Toxicol
December 2024
State Key Laboratory of Cellular Stress Biology, Department of Thoracic Surgery in Xiang'an Hospital of Xiamen University, School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian 361102, China. Electronic address:
Black phosphorus nanomaterials (BPNM) exhibit excellent properties and potential applications in electronics, but workers may face inhalation exposure during BPNM production. In addition, there is a lack of biosafety assessments regarding respiratory exposure to BPNM of different sizes. In this study, we investigated the lung toxicity in mice exposed to 5, 50, 500 μg/kg of black phosphorus quantum dots (BPQDs) and black phosphorus nanosheet (BPNS) via single tracheal instillation.
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